product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
MRE11 (18) Antibody
catalog :
sc-135992
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
18
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:500; loading ...; fig s9a
  • western blot; mouse; 1:100; loading ...; fig s13a
  • western blot; human; 1:100; loading ...; fig s12e
Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
Belmonte Fern xe1 ndez A, Herrero Ru xed z J, Galindo Moreno M, Lim xf3 n Mort xe9 s M, Mora Santos M, S xe1 ez C, et al. Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway. Cell Death Differ. 2022;: pubmed publisher
Na J, Newman J, Then C, Syed J, Vendrell I, Torrecilla I, et al. SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells. Cell Death Dis. 2021;12:165 pubmed publisher
Petsalaki E, Zachos G. An ATM-Chk2-INCENP pathway activates the abscission checkpoint. J Cell Biol. 2021;220: pubmed publisher
Dhoonmoon A, Schleicher E, Clements K, Nicolae C, Moldovan G. Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR. Nucleic Acids Res. 2020;48:7252-7264 pubmed publisher
Zhang Y, Cai L, Wei R, Hu H, Jin W, Zhu X. Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines. Oncol Lett. 2011;2:1327-1332 pubmed
Iofrida C, Melissari E, Mariotti V, Guglielmi C, Guidugli L, Caligo M, et al. Effects on human transcriptome of mutated BRCA1 BRCT domain: a microarray study. BMC Cancer. 2012;12:207 pubmed publisher
Kedar P, Stefanick D, Horton J, Wilson S. Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts. Mol Cancer Res. 2012;10:360-8 pubmed publisher
product information
Catalog Number :
sc-135992
Product Name :
MRE11 (18) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
18
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
MRE11
Specificity :
mouse, rat, human
Uses :
WB, IP, IF
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA