product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
EPAS-1 (190b) Antibody
catalog :
sc-13596
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
190b
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
citations: 15
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; human; loading ...; fig 4c
Shen M, Zhang R, Jia W, Zhu Z, Zhao X, Zhao L, et al. Nuclear scaffold protein p54nrb/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma. Oncogene. 2021;40:4167-4183 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s1a
Lee S, Park K, Lee G, Kim S, Song W, Kwon S, et al. Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss. Exp Mol Med. 2021;53:591-604 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5e
Jassim A, Inman D. Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension. Invest Ophthalmol Vis Sci. 2019;60:1-15 pubmed publisher
  • western blot; human; fig 2
Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed publisher
  • western blot; human; 1:250; fig 3
Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  • western blot; human; 1:500; fig 1
Yu C, Yang S, Fang X, Jiang J, Sun C, Huang T. Hypoxia disrupts the expression levels of circadian rhythm genes in hepatocellular carcinoma. Mol Med Rep. 2015;11:4002-8 pubmed publisher
  • western blot; bovine; loading ...; fig 2b
Medjkane S, Perichon M, Marsolier J, Dairou J, Weitzman J. Theileria induces oxidative stress and HIF1? activation that are essential for host leukocyte transformation. Oncogene. 2014;33:1809-17 pubmed publisher
Bagnall J, Leedale J, Taylor S, Spiller D, White M, Sharkey K, et al. Tight control of hypoxia-inducible factor-? transient dynamics is essential for cell survival in hypoxia. J Biol Chem. 2014;289:5549-64 pubmed publisher
Pelosi M, Lazzarano S, Thoms B, Murphy C. Parathyroid hormone-related protein is induced by hypoxia and promotes expression of the differentiated phenotype of human articular chondrocytes. Clin Sci (Lond). 2013;125:461-70 pubmed publisher
Thoms B, Dudek K, Lafont J, Murphy C. Hypoxia promotes the production and inhibits the destruction of human articular cartilage. Arthritis Rheum. 2013;65:1302-12 pubmed publisher
Gong K, Zhang N, Zhang K, Na Y. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma. Int J Mol Med. 2010;26:907-12 pubmed
Mashiko R, Takano S, Ishikawa E, Yamamoto T, Nakai K, Matsumura A. Hypoxia-inducible factor 1? expression is a prognostic biomarker in patients with astrocytic tumors associated with necrosis on MR image. J Neurooncol. 2011;102:43-50 pubmed publisher
Thoms B, Murphy C. Inhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes. J Biol Chem. 2010;285:20472-80 pubmed publisher
Lafont J, Talma S, Hopfgarten C, Murphy C. Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways. J Biol Chem. 2008;283:4778-86 pubmed
Lafont J, Talma S, Murphy C. Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype. Arthritis Rheum. 2007;56:3297-306 pubmed
product information
Product Name :
EPAS-1 (190b) Antibody
Gene Name :
EPAS1
Size :
200 µg/ml
Catalog Number :
sc-13596
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
EPAS-1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA