product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
MMP-2 (2C1) Antibody
catalog :
sc-13594
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2C1
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; loading ...; fig 5a
Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3l
Pathak T, Gueguinou M, Walter V, Delierneux C, Johnson M, Zhang X, et al. Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1e
Shan L, Liu W, Zhan Y. Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer. Aging (Albany NY). 2019;11:7780-7795 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6d
He M, Shen P, Qiu C, Wang J. miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN. Aging (Albany NY). 2019;11:5744-5756 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 5a
Zhang H, Zhang P, Gao Y, Li C, Wang H, Chen L, et al. Early VEGF inhibition attenuates blood-brain barrier disruption in ischemic rat brains by regulating the expression of MMPs. Mol Med Rep. 2017;15:57-64 pubmed publisher
  • western blot; mouse; loading ...; fig 1f
Burgy O, Bellaye P, Causse S, Beltramo G, Wettstein G, Boutanquoi P, et al. Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin. Respir Res. 2016;17:162 pubmed
  • western blot; human; 1:500; loading ...; fig 2b
Zhang L, Zou W. Inhibition of integrin β1 decreases the malignancy of ovarian cancer cells and potentiates anticancer therapy via the FAK/STAT1 signaling pathway. Mol Med Rep. 2015;12:7869-76 pubmed publisher
  • western blot; rat; 1:500; fig 8
Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher
  • western blot; human; 1:1000; fig 2
Han Y, Lee J, Lee S. Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways. Mol Med Rep. 2015;12:3446-3452 pubmed publisher
  • western blot; human; 1:1000; fig 4
Lin C, Chen P, Hsu L, Kuo D, Chu S, Hsieh Y. Inhibition of the invasion and migration of renal carcinoma 786‑o‑si3 cells in vitro and in vivo by Koelreuteria formosana extract. Mol Med Rep. 2014;10:3334-42 pubmed publisher
  • western blot; human; fig 4a
Raimondi L, Amodio N, Di Martino M, Altomare E, Leotta M, Caracciolo D, et al. Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity. Oncotarget. 2014;5:3039-54 pubmed
  • western blot; human; fig 4
Nie S, Zhou J, Bai F, Jiang B, Chen J, Zhou J. Role of endothelin A receptor in colon cancer metastasis: in vitro and in vivo evidence. Mol Carcinog. 2014;53 Suppl 1:E85-91 pubmed publisher
Xu M, Wei P, Suo M, Hu Y, Ding W, Su L, et al. Brucine Suppresses Vasculogenic Mimicry in Human Triple-Negative Breast Cancer Cell Line MDA-MB-231. Biomed Res Int. 2019;2019:6543230 pubmed publisher
Zhang Q, Agoston A, Pham T, Zhang W, Zhang X, Huo X, et al. Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett's Cells. Gastroenterology. 2019;156:130-144.e10 pubmed publisher
Zeng G, Ding W, Li Y, Sun M, Deng L. Morroniside protects against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression. Exp Ther Med. 2018;16:2229-2234 pubmed publisher
Wang M, Sun Y, Xu J, Lu J, Wang K, Yang D, et al. Preclinical studies using miR-32-5p to suppress clear cell renal cell carcinoma metastasis via altering the miR-32-5p/TR4/HGF/Met signaling. Int J Cancer. 2018;143:100-112 pubmed publisher
Cortes A, Gonsalez S, Rioja L, Oliveira S, Santos A, Prieto M, et al. Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury. Biochim Biophys Acta Mol Basis Dis. 2018;1864:102-114 pubmed publisher
Chen J, Xu W, Chen Y, Xie X, Zhang Y, Ma C, et al. Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling. J Virol. 2017;91: pubmed publisher
Zhu H, Chen X, Chen B, Chen B, Song W, Sun D, et al. Activating transcription factor 4 promotes esophageal squamous cell carcinoma invasion and metastasis in mice and is associated with poor prognosis in human patients. PLoS ONE. 2014;9:e103882 pubmed publisher
Alam M, Shuaib A. Complexity in differentiating the expression of truncated or matured forms of MMP-2 and MMP-9 through zymography in rat brain tissues after acute ischaemic stroke. J Neurosci Methods. 2013;216:22-7 pubmed publisher
Dal Pizzol F, Rojas H, Dos Santos E, Vuolo F, Constantino L, Feier G, et al. Matrix metalloproteinase-2 and metalloproteinase-9 activities are associated with blood-brain barrier dysfunction in an animal model of severe sepsis. Mol Neurobiol. 2013;48:62-70 pubmed publisher
Kim E, Ryu H, Lee H, Kim M. Bevacizumab eye drops delay corneal epithelial wound healing and increase the stromal response to epithelial injury in rats. Clin Exp Ophthalmol. 2013;41:694-701 pubmed publisher
Liu J, Guo S, Li Q, Yang L, Xia Z, Zhang L, et al. Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1. J Neurooncol. 2013;111:245-55 pubmed publisher
Song H, Song C, Wang H, Li C, Yang F, Lu S, et al. Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector. Cancer Gene Ther. 2012;19:875-9 pubmed publisher
Li Y, Zhang Q, Liu Y, Luo Z, Kang L, Qu J, et al. Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways. J Virol. 2012;86:12531-43 pubmed publisher
Cong X, Wu Y, Dai D, Ding M, Zhang Y, Dai Y. Activation of AQP4, p66Shc and endoplasmic reticulum stress is involved in inflammation by carrageenan and is suppressed by argirein, a derivative of rhein. J Pharm Pharmacol. 2012;64:1138-45 pubmed publisher
Marqueti R, Micocci K, Leite R, Selistre de Araujo H. Nandrolone inhibits MMP-2 in the left ventricle of rats. Int J Sports Med. 2012;33:181-5 pubmed publisher
Bhattarai G, Lee Y, Lee N, Yun J, Hwang P, Yi H. c-myb mediates inflammatory reaction against oxidative stress in human breast cancer cell line, MCF-7. Cell Biochem Funct. 2011;29:686-93 pubmed publisher
Rullier A, Gillibert Duplantier J, Costet P, Cubel G, Haurie V, Petibois C, et al. Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 2008;294:G226-35 pubmed
Yu J, Qian H, Li Y, Wang Y, Zhang X, Liang X, et al. Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo. Gynecol Oncol. 2007;106:400-6 pubmed
product information
Product Name :
MMP-2 (2C1) Antibody
Gene Name :
MMP2
Size :
200 µg/ml
Catalog Number :
sc-13594
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
MMP-2
reactive species  :
m, r, h
Application :
WB, IP, IF
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA