product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p-Pol II (8A7) Antibody
catalog :
sc-13583
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
8A7
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human
Saramaki A, Banwell C, Campbell M, Carlberg C. Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res. 2006;34:543-54 pubmed
Sinkkonen L, Malinen M, Saavalainen K, Väisänen S, Carlberg C. Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter. Nucleic Acids Res. 2005;33:2440-51 pubmed
Matilainen J, Malinen M, Turunen M, Carlberg C, Väisänen S. The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells. J Biol Chem. 2010;285:24174-83 pubmed publisher
Kraeussling M, Wagner T, Schartl M. Highly asynchronous and asymmetric cleavage divisions accompany early transcriptional activity in pre-blastula medaka embryos. PLoS ONE. 2011;6:e21741 pubmed
Saavalainen K, Tammi M, Bowen T, Schmitz M, Carlberg C. Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB. J Biol Chem. 2007;282:11530-9 pubmed
Alm-Kristiansen A, Lorenzo P, Molværsmyr A, Matre V, Ledsaak M, Sæther T, et al. PIAS1 interacts with FLASH and enhances its co-activation of c-Myb. Mol Cancer. 2011;10:21 pubmed publisher
Degenhardt T, Matilainen M, Herzig K, Dunlop T, Carlberg C. The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors. J Biol Chem. 2006;281:39607-19 pubmed
Massip A, Arcondeguy T, Touriol C, Basset C, Prats H, Lacazette E. E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV-positive cells. FEBS Lett. 2013;587:3188-94 pubmed publisher
Turunen M, Dunlop T, Carlberg C, Väisänen S. Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene. Nucleic Acids Res. 2007;35:2734-47 pubmed
Dunlop T, Väisänen S, Frank C, Molnár F, Sinkkonen L, Carlberg C. The human peroxisome proliferator-activated receptor delta gene is a primary target of 1alpha,25-dihydroxyvitamin D3 and its nuclear receptor. J Mol Biol. 2005;349:248-60 pubmed
Matilainen M, Malinen M, Saavalainen K, Carlberg C. Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3. Nucleic Acids Res. 2005;33:5521-32 pubmed
Darvekar S, Johnsen S, Eriksen A, Johansen T, Sjøttem E. Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP. Biochem J. 2012;442:65-75 pubmed publisher
Makkonen K, Pasonen-Seppänen S, Törrönen K, Tammi M, Carlberg C. Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling. J Biol Chem. 2009;284:18270-81 pubmed publisher
Degenhardt T, Väisänen S, Rakhshandehroo M, Kersten S, Carlberg C. Peroxisome proliferator-activated receptor alpha controls hepatic heme biosynthesis through ALAS1. J Mol Biol. 2009;388:225-38 pubmed publisher
Makkonen K, Malinen M, Ropponen A, Väisänen S, Carlberg C. Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene. J Mol Biol. 2009;393:261-71 pubmed publisher
Saavalainen K, Pasonen-Seppänen S, Dunlop T, Tammi R, Tammi M, Carlberg C. The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene. J Biol Chem. 2005;280:14636-44 pubmed
product information
Product Name :
p-Pol II (8A7) Antibody
Gene Name :
POLR2A
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13583
Modification :
phosporylated
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
p-Pol II
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
Ser 1801 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA