product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
cytochrome c (7H8) Antibody
catalog :
sc-13560
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7H8
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 47
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:2000; loading ...; fig 7e
Ali A, Kuo W, Kuo C, Lo J, Chen M, Daddam J, et al. E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages. Bioeng Transl Med. 2021;6:e10234 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s1c
Traube F, Özdemir D, Sahin H, Scheel C, Glück A, Geserich A, et al. Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons. Nat Commun. 2021;12:4100 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 6c
Arc Chagnaud C, Py G, Fovet T, Roumanille R, Demangel R, Pagano A, et al. Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning. Front Physiol. 2020;11:71 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2a
Jong A, Wu C, Li J, Sun J, Fabbri M, Wayne A, et al. Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells. J Extracell Vesicles. 2017;6:1294368 pubmed publisher
  • western blot; human; loading ...; fig 4c
Lee J, Westrate L, Wu H, Page C, Voeltz G. Multiple dynamin family members collaborate to drive mitochondrial division. Nature. 2016;540:139-143 pubmed publisher
  • western blot; mouse; 1:500; fig 4
Kumari S, Mehta S, Milledge G, Huang X, Li H, Li P. Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening. Int J Biol Sci. 2016;12:688-700 pubmed publisher
  • western blot; mouse; 1:1000; fig 2b
Viana Huete V, Guillen C, García Aguilar A, García G, Fernandez S, Kahn C, et al. Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity. Endocrinology. 2016;157:1495-511 pubmed publisher
  • western blot; human; 1:1000; tbl 2
Wang G, Fu L, Chen F. Study of the mechanism underlying the inhibitory effects of transglutaminase II on apoptosis in the osteosarcoma MG-63 cell line under hypoxic conditions. Oncol Lett. 2015;10:3425-3428 pubmed
  • western blot; mouse; fig 6
  • western blot; rat; fig 2
Sabirzhanov B, Stoica B, Zhao Z, Loane D, Wu J, Dorsey S, et al. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2016;23:654-68 pubmed publisher
  • immunocytochemistry; human; fig s1
  • western blot; human; fig 1
Fan S, Liu B, Sun L, Lv X, Lin Z, Chen W, et al. Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis. Oncotarget. 2015;6:14885-904 pubmed
  • western blot; human
Hu Z, Zeng Q, Zhang B, Liu H, Wang W. Promotion of p53 expression and reactive oxidative stress production is involved in zerumbone-induced cisplatin sensitization of non-small cell lung cancer cells. Biochimie. 2014;107 Pt B:257-62 pubmed publisher
  • western blot; mouse
  • western blot; human
  • western blot; rat
Sabirzhanov B, Zhao Z, Stoica B, Loane D, Wu J, Borroto C, et al. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. J Neurosci. 2014;34:10055-71 pubmed publisher
  • western blot; mouse
Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher
  • western blot; mouse
Bartolomé A, López Herradón A, Portal Nuñez S, García Aguilar A, Esbrit P, Benito M, et al. Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function. Biochem J. 2013;455:329-37 pubmed publisher
Seidel U, Lüersen K, Huebbe P, Rimbach G. Taurine Enhances Iron-Related Proteins and Reduces Lipid Peroxidation in Differentiated C2C12 Myotubes. Antioxidants (Basel). 2020;9: pubmed publisher
Asokan S, Wang T, Wang M, Lin W. A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway. Aging (Albany NY). 2020;12:7334-7349 pubmed publisher
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, et al. Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter. Aging (Albany NY). 2020;12:611-627 pubmed publisher
Cristofani R, Montagnani Marelli M, Cicardi M, Fontana F, Marzagalli M, Limonta P, et al. Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells. Cell Death Dis. 2018;9:889 pubmed publisher
Sin J, McIntyre L, Stotland A, Feuer R, Gottlieb R. Coxsackievirus B Escapes the Infected Cell in Ejected Mitophagosomes. J Virol. 2017;91: pubmed publisher
Li Z, Mbah N, Maltese W. Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells. Mol Cell Biochem. 2018;439:1-9 pubmed publisher
Sun G, Guzman E, Balasanyan V, Conner C, Wong K, Zhou H, et al. A molecular signature for anastasis, recovery from the brink of apoptotic cell death. J Cell Biol. 2017;216:3355-3368 pubmed publisher
Kwak T, Park S, Kim H, Jeong Y, Kang D. Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells. Onco Targets Ther. 2017;10:137-144 pubmed publisher
Fatfat M, Merhi R, Rahal O, Stoyanovsky D, Zaki A, Haidar H, et al. Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen species. BMC Cancer. 2014;14:527 pubmed publisher
Tusskorn O, Senggunprai L, Prawan A, Kukongviriyapan U, Kukongviriyapan V. Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013;13:571 pubmed publisher
Hernandez G, Thornton C, Stotland A, Lui D, Sin J, Ramil J, et al. MitoTimer: a novel tool for monitoring mitochondrial turnover. Autophagy. 2013;9:1852-61 pubmed publisher
Johnson J, Gonzalez de Mejia E. Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro. Food Chem Toxicol. 2013;60:83-91 pubmed publisher
Basile V, Belluti S, Ferrari E, Gozzoli C, Ganassi S, Quaglino D, et al. bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy. PLoS ONE. 2013;8:e53664 pubmed publisher
Sabirzhanov B, Stoica B, Hanscom M, Piao C, Faden A. Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. J Neurochem. 2012;123:542-54 pubmed publisher
Ma Y, Zhang A, Shi Z, He C, Ding J, Wang X, et al. A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells. Toxicol In Vitro. 2012;26:414-20 pubmed publisher
Ogura K, Yahiro K, Tsutsuki H, Nagasawa S, Yamasaki S, Moss J, et al. Characterization of Cholix toxin-induced apoptosis in HeLa cells. J Biol Chem. 2011;286:37207-15 pubmed publisher
Halder U, Bagchi P, Chattopadhyay S, Dutta D, Chawla Sarkar M. Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. Cell Death Dis. 2011;2:e197 pubmed publisher
Nabzdyk C, Lancero H, Nguyen K, Salek S, Conte M. RNA interference-mediated survivin gene knockdown induces growth arrest and reduced migration of vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2011;301:H1841-9 pubmed publisher
Häggarth L, Hägglöf C, Jaraj S, Wester K, Ponten F, Ostman A, et al. Diagnostic biomarkers of prostate cancer. Scand J Urol Nephrol. 2011;45:60-7 pubmed publisher
Yahiro K, Morinaga N, Moss J, Noda M. Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling. Microb Pathog. 2010;49:153-63 pubmed publisher
Tian H, Yu T, Xu N, Feng C, Zhou L, Luo H, et al. A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway. Cancer Lett. 2010;297:18-30 pubmed publisher
Berger A, Cortese G, Amodeo K, Weihofen A, Letai A, LaVoie M. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Hum Mol Genet. 2009;18:4317-28 pubmed publisher
Liang H, Ran Q, Jang Y, Holstein D, Lechleiter J, McDonald Marsh T, et al. Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria. Free Radic Biol Med. 2009;47:312-20 pubmed publisher
Koeck T, Corbett J, Crabb J, Stuehr D, Aulak K. Glucose-modulated tyrosine nitration in beta cells: targets and consequences. Arch Biochem Biophys. 2009;484:221-31 pubmed
Ahmed K, Fan M, Nantajit D, Cao N, Li J. Cyclin D1 in low-dose radiation-induced adaptive resistance. Oncogene. 2008;27:6738-48 pubmed publisher
Win H, Acevedo Duncan M. Atypical protein kinase C phosphorylates IKKalphabeta in transformed non-malignant and malignant prostate cell survival. Cancer Lett. 2008;270:302-11 pubmed publisher
Masci A, Mastronicola D, Arese M, Piane M, De Amicis A, Blanck T, et al. Control of cell respiration by nitric oxide in Ataxia Telangiectasia lymphoblastoid cells. Biochim Biophys Acta. 2008;1777:66-73 pubmed
Ran Q, Liang H, Ikeno Y, Qi W, Prolla T, Roberts L, et al. Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis. J Gerontol A Biol Sci Med Sci. 2007;62:932-42 pubmed
Renolleau S, Fau S, Goyenvalle C, Joly L, Chauvier D, Jacotot E, et al. Specific caspase inhibitor Q-VD-OPh prevents neonatal stroke in P7 rat: a role for gender. J Neurochem. 2007;100:1062-71 pubmed
Li B, Fan J, Liu X, Qi R, Bo L, Gu J, et al. Suppression of colorectal tumor growth by regulated survivin targeting. J Mol Med (Berl). 2006;84:1077-86 pubmed
Maillard S, Gauduchon J, Marsaud V, Gouilleux F, Connault E, Opolon P, et al. Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma. J Steroid Biochem Mol Biol. 2006;100:67-78 pubmed
Wajapeyee N, Britto R, Ravishankar H, Somasundaram K. Apoptosis induction by activator protein 2alpha involves transcriptional repression of Bcl-2. J Biol Chem. 2006;281:16207-19 pubmed
Trubiani O, Recchioni R, Moroni F, Pizzicannella J, Caputi S, Di Primio R. Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation. J Pineal Res. 2005;39:425-31 pubmed
product information
Product Name :
cytochrome c (7H8) Antibody
Gene Name :
CYCS
Size :
200 µg/ml
Catalog Number :
sc-13560
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
cytochrome c
reactive species  :
m, r, h, equine, avian
Application :
WB, IF, IHC(P)
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA