product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HSP 75 (TR1) Antibody
catalog :
sc-13557
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TR1
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2b
Avolio R, Järvelin A, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, et al. Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Res. 2018;46:12067-12086 pubmed publisher
  • western blot; human; loading ...; fig 4g
Amoroso M, Matassa D, Agliarulo I, Avolio R, Lu H, Sisinni L, et al. TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition. Cell Death Dis. 2016;7:e2522 pubmed publisher
  • western blot; human
Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa D, Esposito F, et al. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells. Int J Oncol. 2014;44:573-82 pubmed publisher
Matassa D, Amoroso M, Lu H, Avolio R, Arzeni D, Procaccini C, et al. Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer. Cell Death Differ. 2016;23:1542-54 pubmed publisher
Guzzo G, Sciacovelli M, Bernardi P, Rasola A. Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells. Oncotarget. 2014;5:11897-908 pubmed
Ciscato F, Sciacovelli M, Villano G, Turato C, Bernardi P, Rasola A, et al. SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I. Oncotarget. 2014;5:2418-27 pubmed
Maddalena F, Sisinni L, Lettini G, Condelli V, Matassa D, Piscazzi A, et al. Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1. Mol Oncol. 2013;7:895-906 pubmed publisher
Maddalena F, Laudiero G, Piscazzi A, Secondo A, Scorziello A, Lombardi V, et al. Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis. Cancer Res. 2011;71:7659-69 pubmed publisher
Amoroso M, Matassa D, Laudiero G, Egorova A, Polishchuk R, Maddalena F, et al. TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins. Cell Death Differ. 2012;19:592-604 pubmed publisher
Landriscina M, Laudiero G, Maddalena F, Amoroso M, Piscazzi A, Cozzolino F, et al. Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents. Cancer Res. 2010;70:6577-86 pubmed publisher
Montesano Gesualdi N, Chirico G, Pirozzi G, Costantino E, Landriscina M, Esposito F. Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis. Stress. 2007;10:342-50 pubmed
product information
Product Name :
HSP 75 (TR1) Antibody
Gene Name :
TRAP1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13557
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
HSP 75
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA