product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
SREBP-2 (1C6) Antibody
catalog :
sc-13552
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1C6
reactivity :
hamsters, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, EMSA
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4f
Aldonza M, Ku J, Hong J, Kim D, Yu S, Lee M, et al. Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020;6:eaav7416 pubmed publisher
  • western blot; human; loading ...; fig 4b
  • western blot; hamsters; loading ...; fig 5c, d
Ochiai A, Miyata S, Shimizu M, Inoue J, Sato R. Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding Proteins. PLoS ONE. 2015;10:e0139799 pubmed publisher
  • immunohistochemistry; human; 1:100
  • western blot; human
Wong T, Lin S, Leung L. The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells. PLoS ONE. 2015;10:e0135637 pubmed publisher
  • EMSA; human; fig 4
  • immunocytochemistry; human; 1:100; fig 3
  • western blot; human; fig 2
Wong T, Lin S, Leung L. The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. Br J Nutr. 2015;113:1844-52 pubmed publisher
  • western blot; mouse; fig 4a
Fukushima M, Villar J, Tsai Morris C, Dufau M. Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25), a negative regulator of luteinizing/chorionic gonadotropin hormone-induced steroidogenesis in Leydig cells: central role of steroidogenic acute regulatory protein (StAR). J Biol Chem. 2011;286:29932-40 pubmed publisher
Syafruddin S, Rodrigues P, Vojtasova E, Patel S, Zaini M, Burge J, et al. A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. Nat Commun. 2019;10:1152 pubmed publisher
Zhang D, Tomisato W, Su L, Sun L, Choi J, Zhang Z, et al. Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proc Natl Acad Sci U S A. 2017;114:E5197-E5206 pubmed publisher
Wilhelm L, Wendling C, Vedie B, Kobayashi T, Chenard M, Tomasetto C, et al. STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites. EMBO J. 2017;36:1412-1433 pubmed publisher
Feig J, Shang Y, Rotllan N, Vengrenyuk Y, Wu C, Shamir R, et al. Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages. PLoS ONE. 2011;6:e28534 pubmed publisher
Xie Z, Liang G, Zhang L, Wang Q, Qu Y, Gao Y, et al. Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin. Acta Pharmacol Sin. 2009;30:1262-75 pubmed publisher
Llorente Cortes V, Costales P, Bernues J, Camino Lopez S, Badimon L. Sterol regulatory element-binding protein-2 negatively regulates low density lipoprotein receptor-related protein transcription. J Mol Biol. 2006;359:950-60 pubmed
product information
Product Name :
SREBP-2 (1C6) Antibody
Gene Name :
SREBF2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13552
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
SREBP-2
reactive species  :
m, r, h
Application :
WB
Epitope :
833-1141 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA