product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Galpha i-2 (L5) Antibody
catalog :
sc-13534
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human
Ha J, Gomathinayagam R, Yan M, Jayaraman M, Ramesh R, Dhanasekaran D. Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth. Genes Cancer. 2015;6:356-364 pubmed
  • western blot; mouse; fig 2d
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nat Med. 2015;21:71-5 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Ward J, Ha J, Jayaraman M, Dhanasekaran D. LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix. Cancer Lett. 2015;356:382-91 pubmed publisher
  • western blot; human
Devi S, Markandeya Y, Maddodi N, Dhingra A, Vardi N, Balijepalli R, et al. Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes. Pigment Cell Melanoma Res. 2013;26:348-56 pubmed publisher
Xiong X, Lee C, Li W, Yu J, Zhu L, Kim Y, et al. Acid Sphingomyelinase regulates the localization and trafficking of palmitoylated proteins. Biol Open. 2019;: pubmed publisher
Liu Q, Li S, Lu C, Yu C, Huang L. G protein γ subunit Gγ13 is essential for olfactory function and aggressive behavior in mice. Neuroreport. 2018;29:1333-1339 pubmed publisher
Luessen D, Sun H, McGinnis M, McCool B, Chen R. Chronic intermittent ethanol exposure selectively alters the expression of G? subunit isoforms and RGS subtypes in rat prefrontal cortex. Brain Res. 2017;1672:106-112 pubmed publisher
Marking S, Krosnowski K, Ogura T, Lin W. Dichotomous Distribution of Putative Cholinergic Interneurons in Mouse Accessory Olfactory Bulb. Front Neuroanat. 2017;11:10 pubmed publisher
Malik R, Ritt M, DeVree B, Neubig R, Sunahara R, Sivaramakrishnan S. Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells. J Biol Chem. 2013;288:17167-78 pubmed publisher
Kapusta D, Pascale C, Kuwabara J, Wainford R. Central nervous system G?i2-subunit proteins maintain salt resistance via a renal nerve-dependent sympathoinhibitory pathway. Hypertension. 2013;61:368-75 pubmed publisher
Kapusta D, Pascale C, Wainford R. Brain heterotrimeric G?i?-subunit protein-gated pathways mediate central sympathoinhibition to maintain fluid and electrolyte homeostasis during stress. FASEB J. 2012;26:2776-87 pubmed publisher
Jeon J, Hong C, Park E, Jeon J, Cho N, Kim I, et al. Selective G?i subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. J Biol Chem. 2012;287:17029-39 pubmed publisher
Suárez R, Fernández Aburto P, Manger P, Mpodozis J. Deterioration of the Gαo vomeronasal pathway in sexually dimorphic mammals. PLoS ONE. 2011;6:e26436 pubmed publisher
Wainford R, Kapusta D. Functional selectivity of central G?-subunit proteins in mediating the cardiovascular and renal excretory responses evoked by central ?(2) -adrenoceptor activation in vivo. Br J Pharmacol. 2012;166:210-20 pubmed publisher
Tam C, Shiu S. Functional interplay between melatonin receptor-mediated antiproliferative signaling and androgen receptor signaling in human prostate epithelial cells: potential implications for therapeutic strategies against prostate cancer. J Pineal Res. 2011;51:297-312 pubmed publisher
Suárez R, Santibáñez R, Parra D, Coppi A, Abrahão L, Sasahara T, et al. Shared and differential traits in the accessory olfactory bulb of caviomorph rodents with particular reference to the semiaquatic capybara. J Anat. 2011;218:558-65 pubmed publisher
Shiu S, Pang B, Tam C, Yao K. Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of G?(s) and G?(q) proteins. J Pineal Res. 2010;49:301-11 pubmed publisher
Suárez R, Villalón A, Künzle H, Mpodozis J. Transposition and Intermingling of Galphai2 and Galphao afferences into single vomeronasal glomeruli in the Madagascan lesser Tenrec Echinops telfairi. PLoS ONE. 2009;4:e8005 pubmed publisher
Suárez R, Mpodozis J. Heterogeneities of size and sexual dimorphism between the subdomains of the lateral-innervated accessory olfactory bulb (AOB) of Octodon degus (Rodentia: Hystricognathi). Behav Brain Res. 2009;198:306-12 pubmed publisher
Aguado Llera D, Arilla Ferreiro E, Chowen J, Argente J, Puebla Jiménez L, Frago L, et al. 17Beta-estradiol protects depletion of rat temporal cortex somatostatinergic system by beta-amyloid. Neurobiol Aging. 2007;28:1396-409 pubmed
Garic Stankovic A, Hernandez M, Chiang P, Debelak Kragtorp K, Flentke G, Armant D, et al. Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cbeta-dependent Ca2+ transient. Alcohol Clin Exp Res. 2005;29:1237-46 pubmed
product information
Product Name :
Galpha i-2 (L5) Antibody
Gene Name :
GNAI2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13534
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Galpha i-2
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
FL (r)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA