| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; loading ...; fig 7a
- western blot; human; loading ...; fig 1c
| Nag J, Kancharla A, Maoz M, Turm H, Agranovich D, Gupta C, et al. Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated ?-catenin stabilization. Oncotarget. 2017;8:38650-38667 pubmed publisher |
- western blot; human; fig 2b
| Indrakusuma I, Romacho T, Eckel J. Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells. Front Pharmacol. 2016;7:497 pubmed publisher |
- flow cytometry; human; 1:100; fig 2 b-e
- immunohistochemistry; human; fig 1a
- western blot; human; 1:100; fig 2
| Johnson J, Miller D, Jiang R, Liu Y, Shi Z, Tarwater L, et al. Protease-activated Receptor-2 (PAR-2)-mediated Nf-κB Activation Suppresses Inflammation-associated Tumor Suppressor MicroRNAs in Oral Squamous Cell Carcinoma. J Biol Chem. 2016;291:6936-45 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; tbl 2
| Lidfeldt J, Bendahl P, Forsare C, Malmström P, Fernö M, Belting M. Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status. PLoS ONE. 2015;10:e0134932 pubmed publisher |
- flow cytometry; human; fig 2
- immunocytochemistry; human; fig 2
| Asokananthan N, Lan R, Graham P, Bakker A, Tokanović A, Stewart G. Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts. Physiol Rep. 2015;3: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1b
| Chen K, Wang C, Tsai M, Wu C, Yang H, Chen L, et al. Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis. 2014;5:e1244 pubmed publisher |
- immunohistochemistry; rat; 1:250
- immunohistochemistry; mouse; 1:250
| Amadesi S, Grant A, Cottrell G, Vaksman N, Poole D, Rozengurt E, et al. Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2. J Comp Neurol. 2009;516:141-56 pubmed publisher |
| Madkhali Y, Featherby S, Collier M, Maraveyas A, Greenman J, Ettelaie C. The Ratio of Factor VIIa:Tissue Factor Content within Microvesicles Determines the Differential Influence on Endothelial Cells. TH Open. 2019;3:e132-e145 pubmed publisher |
| Jung S, Deng Y, Kushmerick C, Asbury C, Hille B, Koh D. Minimizing ATP depletion by oxygen scavengers for single-molecule fluorescence imaging in live cells. Proc Natl Acad Sci U S A. 2018;115:E5706-E5715 pubmed publisher |
| Huesa C, Ortiz A, Dunning L, McGavin L, Bennett L, McIntosh K, et al. Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Ann Rheum Dis. 2016;75:1989-1997 pubmed publisher |
| Roman K, Done J, Schaeffer A, Murphy S, Thumbikat P. Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndrome. Pain. 2014;155:1328-38 pubmed publisher |
| Guo H, Zhao Z, Yang Q, Wang M, Bell R, Wang S, et al. An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway. J Neurosci. 2013;33:6181-90 pubmed publisher |
| Shan J, Oshima T, Chen X, Fukui H, Watari J, Miwa H. Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model. Am J Physiol Gastrointest Liver Physiol. 2012;303:G1105-12 pubmed publisher |
| Chen C, Chen Q, Ouyang Q, Sun J, Liu F, Song D, et al. Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation. J Neuroinflammation. 2012;9:142 pubmed publisher |
| Jobi K, Rauch B, Dangwal S, Freidel K, Doller A, Eberhardt W, et al. Redox regulation of human protease-activated receptor-2 by activated factor X. Free Radic Biol Med. 2011;51:1758-64 pubmed publisher |
| Cooper D, Pechkovsky D, Hackett T, Knight D, Granville D. Granzyme K activates protease-activated receptor-1. PLoS ONE. 2011;6:e21484 pubmed publisher |
| Seo J, Seo J, Chung H, Kim H. Effect of pertussis toxin and herbimycin A on proteinase-activated receptor 2-mediated cyclooxygenase 2 expression in Helicobacter pylori-infected gastric epithelial AGS cells. Yonsei Med J. 2011;52:522-6 pubmed publisher |
| Kagota S, Chia E, McGuire J. Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice. Br J Pharmacol. 2011;164:358-71 pubmed publisher |
| Bhatt D, Ploug K, Ramachandran R, Olesen J, Gupta S. Activation of PAR-2 elicits NO-dependent and CGRP-independent dilation of the dural artery. Headache. 2010;50:1017-30 pubmed publisher |
| Aman M, Hirano M, Kanaide H, Hirano K. Upregulation of proteinase-activated receptor-2 and increased response to trypsin in endothelial cells after exposure to oxidative stress in rat aortas. J Vasc Res. 2010;47:494-506 pubmed publisher |
| Rydén L, Grabau D, Schaffner F, Jönsson P, Ruf W, Belting M. Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer. Int J Cancer. 2010;126:2330-40 pubmed publisher |
| Seo J, Lim J, Yoon J, Kim H. Proteinase-activated receptor-2 mediates the expression of integrin alpha5 and beta1 in Helicobacter pylori-infected gastric epithelial AGS cells. Digestion. 2009;80:40-9 pubmed publisher |
| Inci K, Edebo A, Olbe L, Casselbrant A. Expression of protease-activated-receptor 2 (PAR-2) in human esophageal mucosa. Scand J Gastroenterol. 2009;44:664-71 pubmed publisher |
| Elzer K, Heitzman D, Chernin M, Novak J. Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment. Integr Cancer Ther. 2008;7:282-94 pubmed publisher |
| Abdulrahman M, Maina E, Morris M, Zatyka M, Raval R, Banks R, et al. Identification of novel VHL targets that are associated with the development of renal cell carcinoma. Oncogene. 2007;26:1661-72 pubmed |
| Brueckmann M, Nahrup A, Lang S, Bertsch T, Fukudome K, Liebe V, et al. Recombinant human activated protein C upregulates the release of soluble fractalkine from human endothelial cells. Br J Haematol. 2006;133:550-7 pubmed |
| Kirilak Y, Pavlos N, Willers C, Han R, Feng H, Xu J, et al. Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors. Int J Mol Med. 2006;17:551-8 pubmed |
| Masamune A, Kikuta K, Satoh M, Suzuki N, Shimosegawa T. Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells. J Pharmacol Exp Ther. 2005;312:651-8 pubmed |
