product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ATG5 (C-1) Antibody
catalog :
sc-133158
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-1
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 4b
  • western blot; mouse; 1:2000; loading ...; fig 4d
Wang H, Zhang W, Liu R, Zheng J, Yao X, Chen H, et al. Lack of bombesin receptor-activated protein attenuates bleomycin-induced pulmonary fibrosis in mice. Life Sci Alliance. 2022;5: pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 6a, 7e
Li M, Shen Y, Xiong Y, Wang S, Li C, Bai J, et al. Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5. Cell Prolif. 2021;54:e13136 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Lanzillotta C, Zuliani I, Vasavda C, Snyder S, Paul B, Perluigi M, et al. BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain-Implications for Neurodegeneration. Antioxidants (Basel). 2020;9: pubmed publisher
  • western blot; mouse; fig 2B
Sin J, Andres A, Taylor D, Weston T, Hiraumi Y, Stotland A, et al. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12:369-80 pubmed publisher
  • western blot; human; 1:200; fig 1
De Leo A, Colavita F, Ciccosanti F, Fimia G, Lieberman P, Mattia E. Inhibition of autophagy in EBV-positive Burkitt's lymphoma cells enhances EBV lytic genes expression and replication. Cell Death Dis. 2015;6:e1876 pubmed publisher
  • western blot; human; 1:1000
Wang Z, Li S, Ren R, Li J, Cui X. Recombinant Buckwheat Trypsin Inhibitor Induces Mitophagy by Directly Targeting Mitochondria and Causes Mitochondrial Dysfunction in Hep G2 Cells. J Agric Food Chem. 2015;63:7795-804 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6
Chen K, Wang C, Tsai M, Wu C, Yang H, Chen L, et al. Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis. 2014;5:e1244 pubmed publisher
  • immunocytochemistry; human; 1:500
  • western blot; human; 1:500
Buckingham E, Carpenter J, Jackson W, Grose C. Autophagy and the effects of its inhibition on varicella-zoster virus glycoprotein biosynthesis and infectivity. J Virol. 2014;88:890-902 pubmed publisher
Minami Y, Hoshino A, Higuchi Y, Hamaguchi M, Kaneko Y, Kirita Y, et al. Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion. Nat Commun. 2023;14:4084 pubmed publisher
Zhao X, Liberti R, Jian J, Fu W, Hettinghouse A, Sun Y, et al. Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease. J Mol Med (Berl). 2021;99:1639-1654 pubmed publisher
Devenport S, Singhal R, Radyk M, Taranto J, Kerk S, Chen B, et al. Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress. JCI Insight. 2021;6: pubmed publisher
Gassen N, Niemeyer D, Muth D, Corman V, Martinelli S, Gassen A, et al. SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. Nat Commun. 2019;10:5770 pubmed publisher
Crupi A, Nunnelee J, Taylor D, Thomas A, Vit J, Riera C, et al. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging (Albany NY). 2018;10:3327-3352 pubmed publisher
Zhang Y, Sha R, Zhang L, Zhang W, Jin P, Xu W, et al. Harnessing copper-palladium alloy tetrapod nanoparticle-induced pro-survival autophagy for optimized photothermal therapy of drug-resistant cancer. Nat Commun. 2018;9:4236 pubmed publisher
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, et al. RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly. Cell Death Differ. 2018;25:918-934 pubmed publisher
Shen M, Jiang Y, Guan Z, Cao Y, Li L, Liu H, et al. Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy. Autophagy. 2017;13:1364-1385 pubmed publisher
Bartlett B, Isakson P, Lewerenz J, Sanchez H, Kotzebue R, Cumming R, et al. p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects. Autophagy. 2011;7:572-83 pubmed
Wan X, Zheng F, Zhang L, Miao Y, Man N, Wen L. Autophagy-mediated chemosensitization by cysteamine in cancer cells. Int J Cancer. 2011;129:1087-95 pubmed publisher
Zhang Q, Yang W, Man N, Zheng F, Shen Y, Sun K, et al. Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal. Autophagy. 2009;5:1107-17 pubmed
product information
Catalog Number :
sc-133158
Product Name :
ATG5 (C-1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-1
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
ATG5
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA