product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
eIF2α (D-3) Antibody
catalog :
sc-133132
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-3
reactivity :
fission yeast, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3m, e3e, e3f, e3g
Liu X, Viswanadhapalli S, Kumar S, Lee T, Moore A, Ma S, et al. Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress. Nat Cancer. 2022;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Li L, Yang L, Yang F, Zhao X, Xue S, Gong F. Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. J Inflamm Res. 2021;14:1959-1971 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Li D, Sun S, Fu J, Ouyang S, Zhao Q, Su L, et al. NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. Theranostics. 2021;11:4381-4402 pubmed publisher
  • western blot; human; loading ...; fig s3f
Guillén Boixet J, Kopach A, Holehouse A, Wittmann S, Jahnel M, Schlüßler R, et al. RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell. 2020;181:346-361.e17 pubmed publisher
  • western blot; human; loading ...; fig 2g
Zhang P, Fan B, Yang P, Temirov J, Messing J, Kim H, et al. Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. elife. 2019;8: pubmed publisher
  • western blot; fission yeast; 1:500; fig 3c
Forte G, Davie E, Lie S, Franz Wachtel M, Ovens A, Wang T, et al. Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling. J Cell Sci. 2019;132: pubmed publisher
  • western blot; rat; 1:1000; fig ev5a
  • western blot; human; 1:1000; loading ...; fig ev5a
Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, et al. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. EMBO Mol Med. 2019;11: pubmed publisher
  • western blot; human; 1:100; loading ...; fig 3b
Jeon Y, Kim T, Park D, Nuovo G, Rhee S, Joshi P, et al. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Nat Commun. 2018;9:5110 pubmed publisher
  • western blot; human; loading ...; fig s1e
Avolio R, Järvelin A, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, et al. Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Res. 2018;46:12067-12086 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6d
Nguyen T, Quan X, Xu S, Das R, Cha S, Kong I, et al. Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion. FASEB J. 2016;30:3979-3988 pubmed
  • western blot; mouse; 1:1000; fig s3a
Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Xu S, Nam S, Kim J, Das R, Choi S, Nguyen T, et al. Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress. Cell Death Dis. 2015;6:e1976 pubmed publisher
  • western blot; human
Chang P, Hung C, Wang S, Tsai P, Shih Y, Chen L, et al. Identification and characterization of two novel spliced genes located in the orf47-orf46-orf45 gene locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014;88:10092-109 pubmed publisher
Park D, Yu Y, Kim J, Lee J, Park J, Hong K, et al. Suboptimal Mitochondrial Activity Facilitates Nuclear Heat Shock Responses for Proteostasis and Genome Stability. Mol Cells. 2023;46:374-386 pubmed publisher
Yim J, Park S. Label-Free Target Identification Reveals the Anticancer Mechanism of a Rhenium Isonitrile Complex. Front Chem. 2022;10:850638 pubmed publisher
Tajan M, Hennequart M, Cheung E, Zani F, Hock A, Legrave N, et al. Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy. Nat Commun. 2021;12:366 pubmed publisher
Wang S, Tatman M, Monteiro M. Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD. Acta Neuropathol Commun. 2020;8:164 pubmed publisher
Wang R, Jiang X, Bao P, Qin M, Xu J. Circadian control of stress granules by oscillating EIF2α. Cell Death Dis. 2019;10:215 pubmed publisher
Wang W, Oguz G, Lee P, Bao Y, Wang P, Terp M, et al. KDM4B-regulated unfolded protein response as a therapeutic vulnerability in PTEN-deficient breast cancer. J Exp Med. 2018;215:2833-2849 pubmed publisher
Wang D, Yu H, Xu B, Xu H, Zhang Z, Ren X, et al. TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice. Front Aging Neurosci. 2018;10:72 pubmed publisher
González Almela E, Williams H, Sanz M, Carrasco L. The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells. Front Microbiol. 2018;9:207 pubmed publisher
Deng X, Hackbart M, Mettelman R, O Brien A, Mielech A, Yi G, et al. Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages. Proc Natl Acad Sci U S A. 2017;114:E4251-E4260 pubmed publisher
Hatanaka M, Maier B, Sims E, Templin A, Kulkarni R, Evans Molina C, et al. Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway. Diabetes. 2014;63:3404-15 pubmed publisher
Fang L, Zhou Y, Cao H, Wen P, Jiang L, He W, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE. 2013;8:e60546 pubmed publisher
product information
Catalog Number :
sc-133132
Product Name :
eIF2α (D-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-3
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
eIF2alpha
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA