product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GRK 2 (C-9) Antibody
catalog :
sc-13143
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-9
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4a
Zhao Z, Lee R, Pusapati G, Iyu A, Rohatgi R, Ingham P. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. EMBO Rep. 2016;17:739-52 pubmed publisher
  • western blot; rat; 1:800; fig 5
Yang Y, Ni W, Cai M, Tang L, Wei W. The renoprotective effects of berberine via the EP4-G?s-cAMP signaling pathway in different stages of diabetes in rats. J Recept Signal Transduct Res. 2014;34:445-55 pubmed publisher
Nedi T, White P, Coupar I, Irving H. Effect of the 5-HT4 receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract. BMC Res Notes. 2018;11:362 pubmed publisher
Hernández Pinto A, Puebla Jiménez L, Perianes Cachero A, Arilla Ferreiro E. Vitamin E deficiency impairs the somatostatinergic receptor-effector system and leads to phosphotyrosine phosphatase overactivation and cell death in the rat hippocampus. J Nutr Biochem. 2013;24:848-58 pubmed publisher
Deiss K, Kisker C, Lohse M, Lorenz K. Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2. J Biol Chem. 2012;287:23407-17 pubmed publisher
Aguado Llera D, Puebla Jiménez L, Barrios V, Hernández Pinto A, Arilla Ferreiro E. Role of ethanolamine phosphate in the hippocampus of rats with acute experimental autoimmune encephalomyelitis. Neurochem Int. 2011;58:22-34 pubmed publisher
Zhao W, Tong T, Wang L, Li P, Chang Y, Zhang L, et al. Chicken type II collagen induced immune tolerance of mesenteric lymph node lymphocytes by enhancing beta2-adrenergic receptor desensitization in rats with collagen-induced arthritis. Int Immunopharmacol. 2011;11:12-8 pubmed publisher
Sedaghat K, Tiberi M. Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G protein-coupled receptor kinase 2 and 3. Cell Signal. 2011;23:180-92 pubmed publisher
Nedi T, White P, Coupar I, Irving H. Tissue dependent differences in G-protein coupled receptor kinases associated with 5-HT4 receptor desensitization in the rat gastro-intestinal tract. Biochem Pharmacol. 2011;81:123-33 pubmed publisher
Matuzany Ruban A, Golan M, Miroshnik N, Schreiber G, Avissar S. Normalization of GRK2 protein and mRNA measures in patients with depression predict response to antidepressants. Int J Neuropsychopharmacol. 2010;13:83-91 pubmed publisher
Hernández Pinto A, Puebla Jiménez L, Arilla Ferreiro E. alpha-Tocopherol decreases the somatostatin receptor-effector system and increases the cyclic AMP/cyclic AMP response element binding protein pathway in the rat dentate gyrus. Neuroscience. 2009;162:106-17 pubmed publisher
Burgos Ramos E, Puebla Jiménez L, Arilla Ferreiro E. Minocycline provides protection against beta-amyloid(25-35)-induced alterations of the somatostatin signaling pathway in the rat temporal cortex. Neuroscience. 2008;154:1458-66 pubmed publisher
Sanchez Perez A, Kumar S, Cook D. GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2. Biochem Biophys Res Commun. 2007;359:611-5 pubmed
Wu H, Wei W, Song L, Zhang L, Chen Y, Hu X. Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritis. Int Immunopharmacol. 2007;7:662-73 pubmed
product information
Product Name :
GRK 2 (C-9) Antibody
Gene Name :
ADRBK1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13143
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
GRK 2
reactive species  :
m, r, h
Application :
WB, IP, IF, ELISA
Epitope :
468-689 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA