product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
beta-Arrestin-2 (H-9) Antibody
catalog :
sc-13140
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-9
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3a
Cao C, Zhang Y, Cheng J, Wu F, Niu X, Hu X, et al. β-Arrestin2 Inhibits the Apoptosis and Facilitates the Proliferation of Fibroblast-like Synoviocytes in Diffuse-type Tenosynovial Giant Cell Tumor. Cancer Genomics Proteomics. 2021;18:461-470 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1b
  • western blot; mouse; loading ...; fig 1a, 5a
Chen L, Kong L, Wei X, Wang Y, Wang B, Zhang X, et al. β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury. J Cell Mol Med. 2019;23:3325-3335 pubmed publisher
  • immunoprecipitation; rat; 1:500; loading ...; fig 6b
  • western blot; rat; 1:500; loading ...; fig 6e
Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang R, et al. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci. 2015;128:2271-86 pubmed publisher
  • western blot; rat; 1:500; fig 3
Wu J, Liu B, Tong W, Zhang A, Li F, Lin J, et al. Opioid receptors and associated regulator of G protein signaling are involved in the cathartic colon of rats. Exp Ther Med. 2015;9:1229-1234 pubmed
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Lynch M, Baillie G, Mohamed A, Li X, Maisonneuve C, Klussmann E, et al. RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells. J Biol Chem. 2005;280:33178-89 pubmed
Basso L, Aboushousha R, Fan C, Iftinca M, Melo H, Flynn R, et al. TRPV1 promotes opioid analgesia during inflammation. Sci Signal. 2019;12: pubmed publisher
Eichel K, Jullié D, Barsi Rhyne B, Latorraca N, Masureel M, Sibarita J, et al. Catalytic activation of β-arrestin by GPCRs. Nature. 2018;557:381-386 pubmed publisher
Sangoi M, Lamothe S, Guo J, Yang T, Li W, Avery E, et al. ?-Arrestin-Mediated Regulation of the Human Ether-a-go-go-Related Gene Potassium Channel. Mol Pharmacol. 2017;92:162-174 pubmed publisher
Salazar N, Muñoz D, Kallifatidis G, Singh R, Jordà M, Lokeshwar B. The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Mol Cancer. 2014;13:198 pubmed publisher
Wang S, Gong H, Jiang G, Ye Y, Wu J, You J, et al. Src is required for mechanical stretch-induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-arrestin2 pathways. PLoS ONE. 2014;9:e92926 pubmed publisher
Erickson C, Gul R, Blessing C, Nguyen J, Liu T, Pulakat L, et al. The ?-blocker Nebivolol Is a GRK/?-arrestin biased agonist. PLoS ONE. 2013;8:e71980 pubmed publisher
He J, Tian H, Lee A, Ma M. Postnatal experience modulates functional properties of mouse olfactory sensory neurons. Eur J Neurosci. 2012;36:2452-60 pubmed publisher
Odemis V, Lipfert J, Kraft R, Hajek P, Abraham G, Hattermann K, et al. The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells. Glia. 2012;60:372-81 pubmed publisher
Lee A, He J, Ma M. Olfactory marker protein is critical for functional maturation of olfactory sensory neurons and development of mother preference. J Neurosci. 2011;31:2974-82 pubmed publisher
Pan J, Lewis M, Ketterman J, Clore E, Riley M, Richards K, et al. AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology. 2011;36:1397-411 pubmed publisher
Anthony D, Sin Y, Vadrevu S, Advant N, Day J, Byrne A, et al. ?-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation. Mol Cell Biol. 2011;31:1066-75 pubmed publisher
Chen J, Rusnak M, Lombroso P, Sidhu A. Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. Eur J Neurosci. 2009;29:287-306 pubmed publisher
Macey T, Lowe J, Chavkin C. Mu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neurons. J Biol Chem. 2006;281:34515-24 pubmed
Bruchas M, Macey T, Lowe J, Chavkin C. Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes. J Biol Chem. 2006;281:18081-9 pubmed
Menco B. The fine-structural distribution of G-protein receptor kinase 3, beta-arrestin-2, Ca2+/calmodulin-dependent protein kinase II and phosphodiesterase PDE1C2, and a Cl(-)-cotransporter in rodent olfactory epithelia. J Neurocytol. 2005;34:11-36 pubmed
Macey T, Liu Y, Gurevich V, Neve K. Dopamine D1 receptor interaction with arrestin3 in neostriatal neurons. J Neurochem. 2005;93:128-34 pubmed
product information
Product Name :
beta-Arrestin-2 (H-9) Antibody
Gene Name :
ARRB2
Size :
200 µg/ml
Catalog Number :
sc-13140
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
beta-Arrestin-2
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
N-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA