product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HSP 27 (F-4) Antibody
catalog :
sc-13132
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-4
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 1
Kammoun M, Picard B, Astruc T, Gagaoua M, Aubert D, Bonnet M, et al. The Invalidation of HspB1 Gene in Mouse Alters the Ultrastructural Phenotype of Muscles. PLoS ONE. 2016;11:e0158644 pubmed publisher
  • western blot knockout validation; mouse; 1:1000; tbl 3
Kammoun M, Picard B, Henry Berger J, Cassar Malek I. A network-based approach for predicting Hsp27 knock-out targets in mouse skeletal muscles. Comput Struct Biotechnol J. 2013;6:e201303008 pubmed publisher
  • western blot; bovine; 1:3000; loading ...; tbl 1
Gagaoua M, Couvreur S, Le Bec G, Aminot G, Picard B. Associations among Protein Biomarkers and pH and Color Traits in Longissimus thoracis and Rectus abdominis Muscles in Protected Designation of Origin Maine-Anjou Cull Cows. J Agric Food Chem. 2017;65:3569-3580 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2b,2c
Owen S, Zhao H, Dart A, Wang Y, Ruge F, Gao Y, et al. Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells. Int J Oncol. 2016;49:1839-1847 pubmed publisher
  • western blot; human; loading ...
Zheng G, Li N, Jia X, Peng C, Luo L, Deng Y, et al. MYCN-mediated miR-21 overexpression enhances chemo-resistance via targeting CADM1 in tongue cancer. J Mol Med (Berl). 2016;94:1129-1141 pubmed
  • western blot; human; fig 2
Serban A, Stanca L, Geicu O, Dinischiotu A. AGEs-Induced IL-6 Synthesis Precedes RAGE Up-Regulation in HEK 293 Cells: An Alternative Inflammatory Mechanism?. Int J Mol Sci. 2015;16:20100-17 pubmed publisher
  • western blot; human; 1:200
Å talekar M, Yin X, Rebolj K, Darovic S, Troakes C, Mayr M, et al. Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport. Neuroscience. 2015;293:157-70 pubmed publisher
  • western blot; human
Kim H, Jung G. Reactive oxygen species increase HEPN1 expression via activation of the XBP1 transcription factor. FEBS Lett. 2014;588:4413-21 pubmed publisher
  • western blot; human
Wang Y, Kuramitsu Y, Tokuda K, Baron B, Kitagawa T, Akada J, et al. Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer. PLoS ONE. 2014;9:e109076 pubmed publisher
  • western blot; human; 1:3000
Picard B, Gagaoua M, Micol D, Cassar Malek I, Hocquette J, Terlouw C. Inverse relationships between biomarkers and beef tenderness according to contractile and metabolic properties of the muscle. J Agric Food Chem. 2014;62:9808-18 pubmed publisher
Pasten C, Lozano M, Rocco J, Carrion F, Alvarado C, Liberona J, et al. Aminoguanidine Prevents the Oxidative Stress, Inhibiting Elements of Inflammation, Endothelial Activation, Mesenchymal Markers, and Confers a Renoprotective Effect in Renal Ischemia and Reperfusion Injury. Antioxidants (Basel). 2021;10: pubmed publisher
Miao W, Li L, Zhao Y, Dai X, Chen X, Wang Y. HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. Nat Commun. 2019;10:3613 pubmed publisher
Yanda M, Liu Q, Cebotaru L. A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector. J Biol Chem. 2018;293:11513-11526 pubmed publisher
Kim J, Jung Y, Choi B, Lee N, Lee H, Kwak S, et al. Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules. Oncotarget. 2016;7:53178-53190 pubmed publisher
Leal M, Chung J, Calcagno D, Assumpção P, Demachki S, da Silva I, et al. Differential proteomic analysis of noncardia gastric cancer from individuals of northern Brazil. PLoS ONE. 2012;7:e42255 pubmed publisher
Rocchiccioli S, Ucciferri N, Comelli L, Trivella M, Citti L, Cecchettini A. Proteomics changes in adhesion molecules: a driving force for vascular smooth muscle cell phenotypic switch. Mol Biosyst. 2012;8:1052-9 pubmed publisher
Taga H, Chilliard Y, Meunier B, Chambon C, Picard B, Zingaretti M, et al. Cellular and molecular large-scale features of fetal adipose tissue: is bovine perirenal adipose tissue brown?. J Cell Physiol. 2012;227:1688-700 pubmed publisher
Lomnytska M, Becker S, Hellman K, Hellström A, Souchelnytskyi S, Mints M, et al. Diagnostic protein marker patterns in squamous cervical cancer. Proteomics Clin Appl. 2010;4:17-31 pubmed publisher
Taba K, Kuramitsu Y, Ryozawa S, Yoshida K, Tanaka T, Mori Iwamoto S, et al. KNK437 downregulates heat shock protein 27 of pancreatic cancer cells and enhances the cytotoxic effect of gemcitabine. Chemotherapy. 2011;57:12-6 pubmed publisher
Lomnytska M, Becker S, Bodin I, Olsson A, Hellman K, Hellström A, et al. Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value. Br J Cancer. 2011;104:110-9 pubmed publisher
Staubach S, Razawi H, Hanisch F. Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Proteomics. 2009;9:2820-35 pubmed publisher
Patterson S, Li J, Kang J, Wickrema A, Williams D, Reithmeier R. Loss of specific chaperones involved in membrane glycoprotein biosynthesis during the maturation of human erythroid progenitor cells. J Biol Chem. 2009;284:14547-57 pubmed publisher
Xue Y, Yun D, Esmon A, Zou P, Zuo S, Yu Y, et al. Proteomic dissection of agonist-specific TLR-mediated inflammatory responses on macrophages at subcellular resolution. J Proteome Res. 2008;7:3180-93 pubmed publisher
Lee K, Park J, Yoo W, Gwag T, Lee J, Byun M, et al. Overcoming muscle atrophy in a hibernating mammal despite prolonged disuse in dormancy: proteomic and molecular assessment. J Cell Biochem. 2008;104:642-56 pubmed publisher
Zhang D, Wong L, Koay E. Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer. Mol Cancer. 2007;6:52 pubmed
product information
Product Name :
HSP 27 (F-4) Antibody
Gene Name :
HSPB1
Size :
200 µg/ml
Catalog Number :
sc-13132
Type :
Monoclonal
Host :
mouse monoclonal2a
Antigen :
HSP 27
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
32-108 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA