product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Cdk9 (D-7) Antibody
catalog :
sc-13130
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq
citations: 22
Published Application/Species/Sample/DilutionReference
  • ChIP-Seq; human; loading ...; fig 2c
Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020;577:121-126 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Petkau N, Budak H, Zhou X, Oster H, Eichele G. Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. elife. 2019;8: pubmed publisher
  • western blot; human; 1:500; loading ...; fig s3
Wang R, Cao X, Kulej K, Liu W, Ma T, MacDonald M, et al. Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017;114:E5352-E5361 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 5b
  • western blot; human; loading ...; fig 7c
Ren K, Zhang W, Chen X, Ma Y, Dai Y, Fan Y, et al. An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4. PLoS Pathog. 2016;12:e1005950 pubmed publisher
  • western blot; human; fig 3
Chen Z, Wang Z, Pang J, Yu Y, Bieerkehazhi S, Lu J, et al. Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. Sci Rep. 2016;6:29090 pubmed publisher
  • western blot; human; 1:3000; fig 8
Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
  • immunohistochemistry; human; fig 4
  • western blot; human; fig 2
Han Y, Zhao S, Gong Y, Hou G, Li X, Li L. Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation. Oncotarget. 2016;7:1854-62 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 8a
  • western blot; human; loading ...; fig 8a
Darcis G, Kula A, Bouchat S, Fujinaga K, Corazza F, Ait Ammar A, et al. An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathog. 2015;11:e1005063 pubmed publisher
  • western blot; rat; 1:1000
  • western blot; mouse
Arter J, Wegner M. Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells. J Neurochem. 2015;132:384-93 pubmed publisher
Bunch H, Kim D, Naganuma M, Nakagawa R, Cong A, Jeong J, et al. ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun. 2023;14:8341 pubmed publisher
Bunch H, Jeong J, Kang K, Jo D, Cong A, Kim D, et al. BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ. Open Biol. 2021;11:210221 pubmed publisher
Nagashima R, Hibino K, Ashwin S, Babokhov M, Fujishiro S, Imai R, et al. Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II. J Cell Biol. 2019;218:1511-1530 pubmed publisher
Head P, Zhang H, Bastien A, Koyen A, Withers A, Daddacha W, et al. Sirtuin 2 mutations in human cancers impair its function in genome maintenance. J Biol Chem. 2017;292:9919-9931 pubmed publisher
Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, et al. ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway. Nucleic Acids Res. 2014;42:10037-49 pubmed publisher
Zhu R, Lu X, Pradhan M, Armstrong S, Storchan G, Chow C, et al. A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction. Biochemistry. 2014;53:1753-67 pubmed publisher
Salem T, Gomard T, Court F, Moquet Torcy G, Brockly F, Forné T, et al. Chromatin loop organization of the junb locus in mouse dendritic cells. Nucleic Acids Res. 2013;41:8908-25 pubmed publisher
Tsai W, Wang P, Lin S, Wu I, Ko Y, Chen Y, et al. Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites. Front Microbiol. 2012;3:60 pubmed publisher
Contreras X, Schweneker M, Chen C, McCune J, Deeks S, Martin J, et al. Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells. J Biol Chem. 2009;284:6782-9 pubmed publisher
Wagner K, Wagner N, Ghanbarian H, Grandjean V, Gounon P, Cuzin F, et al. RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse. Dev Cell. 2008;14:962-9 pubmed publisher
Oster B, Bundgaard B, Hupp T, Höllsberg P. Human herpesvirus 6B induces phosphorylation of p53 in its regulatory domain by a CK2- and p38-independent pathway. J Gen Virol. 2008;89:87-96 pubmed
Espinoza Derout J, Wagner M, Shahmiri K, Mascareno E, Chaqour B, Siddiqui M. Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy. Cardiovasc Res. 2007;75:129-38 pubmed
De Falco G, Bellan C, D Amuri A, Angeloni G, Leucci E, Giordano A, et al. Cdk9 regulates neural differentiation and its expression correlates with the differentiation grade of neuroblastoma and PNET tumors. Cancer Biol Ther. 2005;4:277-81 pubmed
product information
Product Name :
Cdk9 (D-7) Antibody
Gene Name :
CDK9
Size :
200 µg/ml
Catalog Number :
sc-13130
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Cdk9
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
204-372 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA