product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
FGFR-3 (B-9) Antibody
catalog :
sc-13121
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-9
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:1000; loading ...; fig s10b
  • western blot; human; 1:1000; fig 2a
Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Koole K, van Kempen P, Swartz J, Peeters T, van Diest P, Koole R, et al. Fibroblast growth factor receptor 3 protein is overexpressed in oral and oropharyngeal squamous cell carcinoma. Cancer Med. 2016;5:275-84 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
Park S, Nam S, Keam B, Kim T, Jeon Y, Lee S, et al. VEGF and Ki-67 Overexpression in Predicting Poor Overall Survival in Adenoid Cystic Carcinoma. Cancer Res Treat. 2016;48:518-26 pubmed publisher
  • immunohistochemistry; human; 1:50
Mansoor A, Akhter A, Pournazari P, Mahe E, Shariff S, Farooq F, et al. Protein Expression for Novel Prognostic Markers (Cyclins D1, D2, D3, B1, B2, ITGβ7, FGFR3, PAX5) Correlate With Previously Reported Gene Expression Profile Patterns in Plasma Cell Myeloma. Appl Immunohistochem Mol Morphol. 2015;23:327-33 pubmed publisher
  • immunohistochemistry; human; 1:25
Kossack N, Terwort N, Wistuba J, Ehmcke J, Schlatt S, Scholer H, et al. A combined approach facilitates the reliable detection of human spermatogonia in vitro. Hum Reprod. 2013;28:3012-25 pubmed publisher
Alijaj N, Moutel S, Gouveia Z, Gray M, Roveri M, Dzhumashev D, et al. Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma. Cancers (Basel). 2020;12: pubmed publisher
Lima N, Atkinson E, Bunney T, Katan M, Huang P. Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations. Int J Mol Sci. 2020;21: pubmed publisher
Guo J, Grow E, Mlcochova H, Maher G, Lindskog C, Nie X, et al. The adult human testis transcriptional cell atlas. Cell Res. 2018;28:1141-1157 pubmed publisher
Best S, Harapas C, Kersbergen A, Rathi V, Asselin Labat M, Sutherland K. FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium. Oncogene. 2018;37:6096-6104 pubmed publisher
Lee C, Moon S, Jeong J, Lee S, Lee M, Yoo S, et al. Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis. Cell Death Dis. 2018;9:401 pubmed publisher
Lehtinen B, Raita A, Kesseli J, Annala M, Nordfors K, Yli Harja O, et al. Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas. BMC Cancer. 2017;17:310 pubmed publisher
Guancial E, Werner L, Bellmunt J, Bamias A, Choueiri T, Ross R, et al. FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder. Cancer Med. 2014;3:835-44 pubmed publisher
Xie Z, Gunaratne J, Cheong L, Liu S, Koh T, Huang G, et al. Plasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma. Oncotarget. 2013;4:1008-18 pubmed
Herrera Abreu M, Pearson A, Campbell J, Shnyder S, Knowles M, Ashworth A, et al. Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer. Cancer Discov. 2013;3:1058-71 pubmed publisher
Balbás Martínez C, Rodriguez Pinilla M, Casanova A, Dominguez O, Pisano D, Gomez G, et al. ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors. PLoS ONE. 2013;8:e62483 pubmed publisher
Ishigami T, Hida Y, Matsudate Y, Murao K, Kubo Y. The involvement of fibroblast growth factor receptor signaling pathways in dermatofibroma and dermatofibrosarcoma protuberans. J Med Invest. 2013;60:106-13 pubmed
von Kopylow K, Staege H, Schulze W, Will H, Kirchhoff C. Fibroblast growth factor receptor 3 is highly expressed in rarely dividing human type A spermatogonia. Histochem Cell Biol. 2012;138:759-72 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Marshall M, Hinz T, Kono S, Singleton K, Bichon B, Ware K, et al. Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells. Clin Cancer Res. 2011;17:5016-25 pubmed publisher
Ware K, Marshall M, Heasley L, Marek L, Hinz T, Hercule P, et al. Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression. PLoS ONE. 2010;5:e14117 pubmed publisher
Zingone A, Cultraro C, Shin D, Bean C, Morse H, Janz S, et al. Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. Leukemia. 2010;24:1171-8 pubmed publisher
Hida Y, Kubo Y, Nishio Y, Murakami S, Fukumoto D, Sayama K, et al. Malignant acanthosis nigricans with enhanced expression of fibroblast growth factor receptor 3. Acta Derm Venereol. 2009;89:435-7 pubmed publisher
Karlou M, Saetta A, Korkolopoulou P, Levidou G, Papanastasiou P, Boltetsou E, et al. Activation of extracellular regulated kinases (ERK1/2) predicts poor prognosis in urothelial bladder carcinoma and is not associated with B-Raf gene mutations. Pathology. 2009;41:327-34 pubmed publisher
Hida Y, Kubo Y, Arase S. Activation of fibroblast growth factor receptor 3 and oncogene-induced senescence in skin tumours. Br J Dermatol. 2009;160:1258-63 pubmed publisher
Dawson M, Opat S, Taouk Y, Donovan M, Zammit M, Monaghan K, et al. Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma. Clin Cancer Res. 2009;15:714-22 pubmed publisher
Larson A, Cook J. Fibroblast growth factor receptor 3 (FGFR3) expression in malignant lymphomas. Appl Immunohistochem Mol Morphol. 2008;16:322-5 pubmed publisher
Chang H, Stewart A, Qi X, Li Z, Yi Q, Trudel S. Immunohistochemistry accurately predicts FGFR3 aberrant expression and t(4;14) in multiple myeloma. Blood. 2005;106:353-5 pubmed
product information
Product Name :
FGFR-3 (B-9) Antibody
Gene Name :
FGFR3
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13121
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
FGFR-3
reactive species  :
human
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
25-124 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA