product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HSP 90alpha/beta (F-8) Antibody
catalog :
sc-13119
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-8
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, RNA immunoprecipitation
citations: 107
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6c
Lopez V, Park B, Nowak D, Sreelatha A, Zembek P, Fernandez J, et al. A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity. Cell. 2019;179:205-218.e21 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
Stefanius K, Servage K, de Souza Santos M, Gray H, Toombs J, Chimalapati S, et al. Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Morris K, Corbett A. The polyadenosine RNA-binding protein ZC3H14 interacts with the THO complex and coordinately regulates the processing of neuronal transcripts. Nucleic Acids Res. 2018;46:6561-6575 pubmed publisher
  • RNA immunoprecipitation; human; loading ...; fig s9d
  • western blot; mouse; fig 1c
Hattori A, Tsunoda M, Konuma T, Kobayashi M, Nagy T, Glushka J, et al. Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia. Nature. 2017;545:500-504 pubmed publisher
  • western blot; human; loading ...; fig 1f
de la Mare J, Jurgens T, Edkins A. Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model. BMC Cancer. 2017;17:202 pubmed publisher
  • western blot; human; loading ...; fig 4d
Voráčová K, Hajek J, Mares J, Urajová P, Kuzma M, Cheel J, et al. The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells. PLoS ONE. 2017;12:e0172850 pubmed publisher
  • western blot; human; loading ...; fig 3b
Hattori A, McSkimming D, Kannan N, Ito T. RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia. Leuk Res. 2017;54:47-54 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Chavan R, Preitner N, Okabe T, Strittmatter L, Xu C, Ripperger J, et al. REV-ERB? regulates Fgf21 expression in the liver via hepatic nuclear factor 6. Biol Open. 2017;6:1-7 pubmed publisher
  • western blot; human; loading ...; fig 1h
Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
  • western blot; mouse; fig 2
Hinds T, Burns K, Hosick P, McBeth L, Nestor Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3? Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) ?. J Biol Chem. 2016;291:25179-25191 pubmed
  • immunoprecipitation; mouse; loading ...; fig 2c
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3
  • western blot; mouse; 1:1000; loading ...; fig 2c
Okabe T, Chavan R, Fonseca Costa S, Brenna A, Ripperger J, Albrecht U. REV-ERB? influences the stability and nuclear localization of the glucocorticoid receptor. J Cell Sci. 2016;129:4143-4154 pubmed
  • western blot; mouse; fig 3d
Myasnikov A, Kundhavai Natchiar S, Nebout M, Hazemann I, Imbert V, Khatter H, et al. Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun. 2016;7:12856 pubmed publisher
  • western blot; human; fig 6
Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed publisher
  • western blot; mouse; fig 2
Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig s1c
Lee J, Takahama S, Zhang G, Tomarev S, Ye Y. Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells. Nat Cell Biol. 2016;18:765-76 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher
  • western blot; human; 1:1000
Webber P, Park C, Qui M, Ramalingam S, Khuri F, Fu H, et al. Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience. 2015;2:765-776 pubmed
  • western blot; human; fig 3
Hedstrom E, Pederiva C, Farnebo J, Nodin B, Jirstrom K, Brennan D, et al. Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome. Cell Death Dis. 2015;6:e1892 pubmed publisher
  • western blot; human; fig 6
Brito H, Martins A, Lavrado J, Mendes E, Francisco A, Santos S, et al. Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives. PLoS ONE. 2015;10:e0126891 pubmed publisher
  • western blot; human
Yeh J, Kreimer S, Walker S, Emori M, Krystal H, Richardson A, et al. Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer. Genes Cancer. 2015;6:153-68 pubmed
  • western blot; mouse; 1:1000; fig 5
Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, et al. Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model. PLoS ONE. 2015;10:e0126483 pubmed publisher
  • western blot; human; fig 4a
Wang Y, Kuramitsu Y, Kitagawa T, Tokuda K, Baron B, Akada J, et al. The Histone Deacetylase Inhibitor Valproic Acid Sensitizes Gemcitabine-Induced Cytotoxicity in Gemcitabine-Resistant Pancreatic Cancer Cells Possibly Through Inhibition of the DNA Repair Protein Gamma-H2AX. Target Oncol. 2015;10:575-81 pubmed publisher
  • western blot; mouse; 1:2000
López Bernardo E, Anedda A, Sánchez Pérez P, Acosta Iborra B, Cadenas S. 4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes. Free Radic Biol Med. 2015;88:427-438 pubmed publisher
  • western blot; human; fig 5
Shrestha S, Sun Y, Lufkin T, Kraus P, Or Y, Garcia Y, et al. Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity. Int J Biol Sci. 2015;11:434-47 pubmed publisher
  • western blot; human
Tristante E, Martínez C, Jiménez S, Mora L, Carballo F, Martínez Lacaci I, et al. Association of a characteristic membrane pattern of annexin A2 with high invasiveness and nodal status in colon adenocarcinoma. Transl Res. 2015;166:196-206 pubmed publisher
  • western blot; human
Wnorowski A, Sadowska M, Paul R, Singh N, Boguszewska Czubara A, Jimenez L, et al. Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells. Cell Signal. 2015;27:997-1007 pubmed publisher
  • immunoprecipitation; human; fig 4
Guo Y, Liu J, Elfenbein S, Ma Y, Zhong M, Qiu C, et al. Characterization of the mammalian miRNA turnover landscape. Nucleic Acids Res. 2015;43:2326-41 pubmed publisher
  • western blot; human
Park S, Park J, Kim Y, Song S, Kwon H, Lee Y. Suberoylanilide hydroxamic acid induces ROS-mediated cleavage of HSP90 in leukemia cells. Cell Stress Chaperones. 2015;20:149-57 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
  • western blot; human; 1:1000
Rappa F, Sciume C, Lo Bello M, Bavisotto C, Marino Gammazza A, Barone R, et al. Comparative analysis of Hsp10 and Hsp90 expression in healthy mucosa and adenocarcinoma of the large bowel. Anticancer Res. 2014;34:4153-9 pubmed
  • western blot; mouse; fig 5
Rogon C, Ulbricht A, Hesse M, Alberti S, Vijayaraj P, Best D, et al. HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis. Mol Biol Cell. 2014;25:2260-71 pubmed publisher
  • western blot; human; loading ...; fig 1c
Zahreddine H, Culjkovic Kraljacic B, Assouline S, Gendron P, Romeo A, Morris S, et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014;511:90-3 pubmed publisher
  • western blot; mouse
Sun Y, Chung H, Woo A, Lin V. Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor ? via distinct mechanisms. Biochim Biophys Acta. 2014;1843:2067-78 pubmed publisher
  • western blot; human
Havel J, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 2015;34:1487-98 pubmed publisher
  • western blot; human; loading ...; fig 5c
Walker S, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, et al. The transcriptional modulator BCL6 as a molecular target for breast cancer therapy. Oncogene. 2015;34:1073-82 pubmed publisher
  • western blot; human; fig 3
Liu S, Walker S, Nelson E, Cerulli R, Xiang M, Toniolo P, et al. Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2. Mol Cancer Ther. 2014;13:1194-205 pubmed publisher
  • western blot; rat
Marshall K, Edwards M, Krenz M, Davis J, Baines C. Proteomic mapping of proteins released during necrosis and apoptosis from cultured neonatal cardiac myocytes. Am J Physiol Cell Physiol. 2014;306:C639-47 pubmed publisher
  • western blot; human
Lee J, Kim W, Gygi S, Ye Y. Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation. J Biol Chem. 2014;289:3510-7 pubmed publisher
  • western blot; human; 1:1000
Ipenberg I, Guttmann Raviv N, Khoury H, Kupershmit I, Ayoub N. Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase. J Biol Chem. 2013;288:14681-7 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Lyko F, Foret S, Kucharski R, Wolf S, Falckenhayn C, Maleszka R. The honey bee epigenomes: differential methylation of brain DNA in queens and workers. PLoS Biol. 2010;8:e1000506 pubmed publisher
Yenerall P, Das A, Wang S, Kollipara R, Li L, Villalobos P, et al. RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer. Cell Chem Biol. 2019;: pubmed publisher
Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O. FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers (Basel). 2019;11: pubmed publisher
Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature. 2019;: pubmed publisher
Wang L, Zhang L, Li L, Jiang J, Zheng Z, Shang J, et al. Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer. Sci Adv. 2019;5:eaax2277 pubmed publisher
Miao W, Li L, Zhao Y, Dai X, Chen X, Wang Y. HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. Nat Commun. 2019;10:3613 pubmed publisher
Bornelöv S, Selmi T, Flad S, Dietmann S, Frye M. Codon usage optimization in pluripotent embryonic stem cells. Genome Biol. 2019;20:119 pubmed publisher
Ungefroren H, Otterbein H, Fiedler C, Mihara K, Hollenberg M, Gieseler F, et al. RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5. Cancers (Basel). 2019;11: pubmed publisher
Woosley A, Dalton A, Hussey G, Howley B, Mohanty B, Grelet S, et al. TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis. Oncogene. 2019;38:3794-3811 pubmed publisher
Lambert J, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla Reimand L, et al. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. 2019;73:621-638.e17 pubmed publisher
Nogami A, Okada K, Ishida S, Akiyama H, Umezawa Y, Miura O. Inhibition of the STAT5/Pim Kinase Axis Enhances Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive AML Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway. Transl Oncol. 2019;12:336-349 pubmed publisher
Ventimiglia L, Cuesta Geijo M, Martinelli N, Caballe A, Macheboeuf P, Miguet N, et al. CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope. Dev Cell. 2018;47:547-563.e6 pubmed publisher
Ruiz Estévez M, Staats J, Paatela E, Munson D, Katoku Kikyo N, Yuan C, et al. Promotion of Myoblast Differentiation by Fkbp5 via Cdk4 Isomerization. Cell Rep. 2018;25:2537-2551.e8 pubmed publisher
Sustic T, van Wageningen S, Bosdriesz E, Reid R, Dittmar J, Lieftink C, et al. A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers. Genome Med. 2018;10:90 pubmed publisher
Niu X, Su L, Qi S, Gao Z, Zhang Q, Zhang S. GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway. Cell Death Dis. 2018;9:971 pubmed publisher
Boel N, Hunter M, Edkins A. LRP1 is required for novobiocin-mediated fibronectin turnover. Sci Rep. 2018;8:11438 pubmed publisher
Shao H, Li X, Moses M, Gilbert L, Kalyanaraman C, Young Z, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018;61:6163-6177 pubmed publisher
Mali G, Yeyati P, Mizuno S, Dodd D, Tennant P, Keighren M, et al. ZMYND10 functions in a chaperone relay during axonemal dynein assembly. elife. 2018;7: pubmed publisher
Noguchi K, Dincman T, Dalton A, Howley B, McCall B, Mohanty B, et al. Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). J Biol Chem. 2018;293:11401-11414 pubmed publisher
Liu X, Main D, Ma Y, He B. Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex. J Virol. 2018;92: pubmed publisher
Ohanna M, Cerezo M, Nottet N, Bille K, Didier R, Béranger G, et al. Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype. Genes Dev. 2018;32:448-461 pubmed publisher
Okada K, Nogami A, Ishida S, Akiyama H, Chen C, Umezawa Y, et al. FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway. Oncotarget. 2018;9:8870-8886 pubmed publisher
Bai M, Vozdek R, Hnizda A, Jiang C, Wang B, Kuchar L, et al. Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection. Nat Commun. 2018;9:897 pubmed publisher
Howley B, Link L, Grelet S, El Sabban M, Howe P. A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer. Oncogene. 2018;37:1308-1325 pubmed publisher
Madrigal A, Tan L, Zhao Y. Expression regulation and functional analysis of RGS2 and RGS4 in adipogenic and osteogenic differentiation of human mesenchymal stem cells. Biol Res. 2017;50:43 pubmed publisher
Umezawa Y, Akiyama H, Okada K, Ishida S, Nogami A, Oshikawa G, et al. Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). J Biol Chem. 2017;292:19639-19655 pubmed publisher
Ayre D, Chute I, Joy A, Barnett D, Hogan A, Grüll M, et al. CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo. Sci Rep. 2017;7:8642 pubmed publisher
Vest K, Phillips B, Banerjee A, Apponi L, Dammer E, Xu W, et al. Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology. Hum Mol Genet. 2017;26:3235-3252 pubmed publisher
Mimmler M, Peter S, Kraus A, Stroh S, Nikolova T, Seiwert N, et al. DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP. Nucleic Acids Res. 2016;44:10259-10276 pubmed
Kim J, Jung Y, Choi B, Lee N, Lee H, Kwak S, et al. Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules. Oncotarget. 2016;7:53178-53190 pubmed publisher
Umezawa Y, Kurosu T, Akiyama H, Wu N, Nogami A, Nagao T, et al. Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells. Oncotarget. 2016;7:44448-44461 pubmed publisher
Asp N, Kvalvaag A, Sandvig K, Pust S. Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins. Oncotarget. 2016;7:25443-60 pubmed publisher
Panda A, Abdelmohsen K, Martindale J, Di Germanio C, Yang X, Grammatikakis I, et al. Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis. Nucleic Acids Res. 2016;44:2393-408 pubmed publisher
Jirakanwisal K, Srisutthisamphan K, Thepparit C, Suptawiwat O, Auewarakul P, Paemanee A, et al. Identification of Hsp90 as a species independent H5N1 avian influenza A virus PB2 interacting protein. Comp Immunol Microbiol Infect Dis. 2015;43:28-35 pubmed publisher
Jiang Q, Cheng K, Mei X, Qiu J, Zhang W, Xue Y, et al. Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine. Oncotarget. 2015;6:32790-804 pubmed publisher
Chen X, Xie F, Zhu X, Lin F, Pan S, Gong L, et al. Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer. Oncotarget. 2015;6:14926-39 pubmed
Caito S, Zeng H, Aschner J, Aschner M. Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS. PLoS ONE. 2014;9:e98161 pubmed publisher
Hunter M, O Hagan K, Kenyon A, Dhanani K, Prinsloo E, Edkins A. Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells. PLoS ONE. 2014;9:e86842 pubmed publisher
Rosilio C, Lounnas N, Nebout M, Imbert V, Hagenbeek T, Spits H, et al. The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells. Cancer Lett. 2013;336:114-26 pubmed publisher
Chen M, Sato P, Chuprun J, Peroutka R, Otis N, Ibetti J, et al. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. Circ Res. 2013;112:1121-34 pubmed publisher
Rappa F, Cappello F, Halatsch M, Scheuerle A, Kast R. Aldehyde dehydrogenase and HSP90 co-localize in human glioblastoma biopsy cells. Biochimie. 2013;95:782-6 pubmed publisher
Barrell W, Szabo Rogers H, Liu K. Novel reporter alleles of GSK-3? and GSK-3?. PLoS ONE. 2012;7:e50422 pubmed publisher
Madrigal Matute J, Fernandez García C, Gomez Guerrero C, Lopez Franco O, Munoz Garcia B, Egido J, et al. HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis. Cardiovasc Res. 2012;95:116-23 pubmed publisher
Tomasello G, Sciume C, Rappa F, Rodolico V, Zerilli M, Martorana A, et al. Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy. Eur J Histochem. 2011;55:e38 pubmed publisher
Milutinović D, Macut D, Bozic I, Nestorov J, Damjanovic S, Matic G. Hypothalamic-pituitary-adrenocortical axis hypersensitivity and glucocorticoid receptor expression and function in women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes. 2011;119:636-43 pubmed publisher
Pietschmann K, Buchwald M, Müller S, Knauer S, Kögl M, Heinzel T, et al. Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1. Int J Biochem Cell Biol. 2012;44:132-8 pubmed publisher
Falahatpisheh M, Nanez A, Ramos K. AHR regulates WT1 genetic programming during murine nephrogenesis. Mol Med. 2011;17:1275-84 pubmed publisher
Fukushima T, Okajima H, Yamanaka D, Ariga M, Nagata S, Ito A, et al. HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells. Mol Cell Endocrinol. 2011;344:81-9 pubmed publisher
Pozo F, Oda T, Sekimoto T, Murakumo Y, Masutani C, Hanaoka F, et al. Molecular chaperone Hsp90 regulates REV1-mediated mutagenesis. Mol Cell Biol. 2011;31:3396-409 pubmed publisher
Mahmoudi S, Henriksson S, Weibrecht I, Smith S, Söderberg O, Stromblad S, et al. WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. PLoS Biol. 2010;8:e1000521 pubmed publisher
Buchwald M, Pietschmann K, Muller J, Bohmer F, Heinzel T, Krämer O. Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation. Leukemia. 2010;24:1412-21 pubmed publisher
Madrigal Matute J, Lopez Franco O, Blanco Colio L, Munoz Garcia B, Ramos Mozo P, Ortega L, et al. Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis. Cardiovasc Res. 2010;86:330-7 pubmed publisher
Elaković I, Vasiljević D, Adzic M, Djordjevic A, Djordjevic J, Radojcic M, et al. Sexually dimorphic functional alterations of rat hepatic glucocorticoid receptor in response to fluoxetine. Eur J Pharmacol. 2010;632:79-85 pubmed publisher
Tanikawa C, Ueda K, Nakagawa H, Yoshida N, Nakamura Y, Matsuda K. Regulation of protein Citrullination through p53/PADI4 network in DNA damage response. Cancer Res. 2009;69:8761-9 pubmed publisher
Corsino P, HORENSTEIN N, Ostrov D, Rowe T, Law M, Barrett A, et al. A novel class of cyclin-dependent kinase inhibitors identified by molecular docking act through a unique mechanism. J Biol Chem. 2009;284:29945-55 pubmed publisher
Liangliang X, Yonghui H, Shunmei E, Shoufang G, Wei Z, Jiangying Z. Dominant-positive HSF1 decreases alpha-synuclein level and alpha-synuclein-induced toxicity. Mol Biol Rep. 2010;37:1875-81 pubmed publisher
Konstantakou E, Voutsinas G, Karkoulis P, Aravantinos G, Margaritis L, Stravopodis D. Human bladder cancer cells undergo cisplatin-induced apoptosis that is associated with p53-dependent and p53-independent responses. Int J Oncol. 2009;35:401-16 pubmed
Zhao Y, Gong S, Shunmei E, Zou J. Induction of macroautophagy by heat. Mol Biol Rep. 2009;36:2323-7 pubmed publisher
Stravopodis D, Karkoulis P, Konstantakou E, Melachroinou S, Lampidonis A, Anastasiou D, et al. Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines. Int J Oncol. 2009;34:137-60 pubmed
Wolf I, Periyasamy S, Hinds T, Yong W, Shou W, SANCHEZ E. Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity. J Steroid Biochem Mol Biol. 2009;113:36-45 pubmed publisher
Kijanka G, Ipcho S, Baars S, Chen H, Hadley K, Beveridge A, et al. Rapid characterization of binding specificity and cross-reactivity of antibodies using recombinant human protein arrays. J Immunol Methods. 2009;340:132-7 pubmed publisher
Di Felice V, Cappello F, Montalbano A, Ardizzone N, De Luca A, Macaluso F, et al. HSP90 and eNOS partially co-localize and change cellular localization in relation to different ECM components in 2D and 3D cultures of adult rat cardiomyocytes. Biol Cell. 2007;99:689-99 pubmed
Kuwahara K, Wang Y, McAnally J, Richardson J, Bassel Duby R, Hill J, et al. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest. 2006;116:3114-26 pubmed
Uchiyama Y, Takeda N, Mori M, Terada K. Heat shock protein 40/DjB1 is required for thermotolerance in early phase. J Biochem. 2006;140:805-12 pubmed
Rubio N, Sanz Rodriguez F. Induction of the CXCL1 (KC) chemokine in mouse astrocytes by infection with the murine encephalomyelitis virus of Theiler. Virology. 2007;358:98-108 pubmed
Hermann P, Dobbelaere D. Theileria-induced constitutive IKK activation is independent of functional Hsp90. FEBS Lett. 2006;580:5023-8 pubmed
Gottschalg E, Moore N, Ryan A, Travis L, Waller R, Pratt S, et al. Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression: implications for fingerprint profiling of cytotoxicity. Chem Biol Interact. 2006;161:251-61 pubmed
Fan G, Zhou H, Yang H, Chen S. Heat shock proteins reduce alpha-synuclein aggregation induced by MPP+ in SK-N-SH cells. FEBS Lett. 2006;580:3091-8 pubmed
Mohan J, Gandhi A, Bhavya B, Rashmi R, Karunagaran D, Indu R, et al. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. J Biol Chem. 2006;281:17599-611 pubmed
product information
Product Name :
HSP 90alpha/beta (F-8) Antibody
Gene Name :
HSP90AA1, HSP90AB1, HSP90B1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-13119
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
HSP 90alpha/beta
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
610-723 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA