product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
neuropilin-2 (C-9) Antibody
catalog :
sc-13117
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-9
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 6b
Agrawal P, Fontanals Cirera B, Sokolova E, Jacob S, Vaiana C, Argibay D, et al. A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis. Cancer Cell. 2017;31:804-819.e7 pubmed publisher
  • immunohistochemistry; rat; 1:50; fig 2
  • western blot; rat; fig 6
Pellet Many C, Mehta V, Fields L, Mahmoud M, Lowe V, Evans I, et al. Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res. 2015;108:288-98 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 1
Ji T, Guo Y, Kim K, McQueen P, Ghaffar S, Christ A, et al. Neuropilin-2 expression is inhibited by secreted Wnt antagonists and its down-regulation is associated with reduced tumor growth and metastasis in osteosarcoma. Mol Cancer. 2015;14:86 pubmed publisher
  • western blot; human
Epis M, Giles K, Candy P, Webster R, Leedman P. miR-331-3p regulates expression of neuropilin-2 in glioblastoma. J Neurooncol. 2014;116:67-75 pubmed publisher
Smolkin T, Nir Zvi I, Duvshani N, Mumblat Y, Kessler O, Neufeld G. Complexes of plexin-A4 and plexin-D1 convey semaphorin-3C signals to induce cytoskeletal collapse in the absence of neuropilins. J Cell Sci. 2018;131: pubmed publisher
Po A, Silvano M, Miele E, Capalbo C, Eramo A, Salvati V, et al. Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma. Oncogene. 2017;36:4641-4652 pubmed publisher
Dutta S, Roy S, Polavaram N, Stanton M, Zhang H, Bhola T, et al. Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology. Cancer Res. 2016;76:418-28 pubmed publisher
Nakayama H, Bruneau S, Kochupurakkal N, Coma S, Briscoe D, Klagsbrun M. Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo. Sci Rep. 2015;5:11789 pubmed publisher
Keck B, Wach S, Taubert H, Zeiler S, Ott O, Kunath F, et al. Neuropilin-2 and its ligand VEGF-C predict treatment response after transurethral resection and radiochemotherapy in bladder cancer patients. Int J Cancer. 2015;136:443-51 pubmed publisher
Sabag A, Bode J, Fink D, Kigel B, Kugler W, Neufeld G. Semaphorin-3D and semaphorin-3E inhibit the development of tumors from glioblastoma cells implanted in the cortex of the brain. PLoS ONE. 2012;7:e42912 pubmed publisher
Bielenberg D, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, et al. Increased smooth muscle contractility in mice deficient for neuropilin 2. Am J Pathol. 2012;181:548-59 pubmed publisher
Vintonenko N, Pelaez Garavito I, Buteau Lozano H, Toullec A, Lidereau R, Perret G, et al. Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions. Cell Adh Migr. 2011;5:332-43 pubmed publisher
Herzog B, Pellet Many C, Britton G, Hartzoulakis B, Zachary I. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation. Mol Biol Cell. 2011;22:2766-76 pubmed publisher
Wu F, Zhou Q, Yang J, Duan G, Ou J, Zhang R, et al. Endogenous axon guiding chemorepulsant semaphorin-3F inhibits the growth and metastasis of colorectal carcinoma. Clin Cancer Res. 2011;17:2702-11 pubmed publisher
Stine M, Wang C, Moriarty W, Ryu B, Cheong R, Westra W, et al. Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction. Cancer Res. 2011;71:2433-44 pubmed publisher
product information
Catalog Number :
sc-13117
Product Name :
neuropilin-2 (C-9) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-9
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
neuropilin-2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA