product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
AP-2γ (6E4/4) Antibody
catalog :
sc-12762
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
AP
clone name :
6E4/4
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 35
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s5c
Alim I, Caulfield J, Chen Y, Swarup V, Geschwind D, Ivanova E, et al. Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell. 2019;177:1262-1279.e25 pubmed publisher
  • immunohistochemistry; human; 1:40
Mosbech C, Svingen T, Nielsen J, Toft B, Rechnitzer C, Petersen B, et al. Expression pattern of clinically relevant markers in paediatric germ cell- and sex-cord stromal tumours is similar to adult testicular tumours. Virchows Arch. 2014;465:567-77 pubmed publisher
Varberg K, Domínguez E, Koseva B, Varberg J, McNally R, Moreno Irusta A, et al. Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape. Nat Commun. 2023;14:4826 pubmed publisher
Li X, Chen P, Ji J, Duan Q, Cao J, Huang R, et al. Rhox6 regulates the expression of distinct target genes to mediate mouse PGCLC formation and ESC self-renewal. Cell Biosci. 2023;13:145 pubmed publisher
Naama M, Rahamim M, Zayat V, Sebban S, Radwan A, Orzech D, et al. Pluripotency-independent induction of human trophoblast stem cells from fibroblasts. Nat Commun. 2023;14:3359 pubmed publisher
Frost J, Amante S, Okae H, Jones E, Ashley B, Lewis R, et al. Regulation of human trophoblast gene expression by endogenous retroviruses. Nat Struct Mol Biol. 2023;30:527-538 pubmed publisher
Madrigal P, Deng S, Feng Y, Militi S, Goh K, Nibhani R, et al. Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation. Nat Commun. 2023;14:405 pubmed publisher
Kenny C, Dilshat R, Seberg H, Van Otterloo E, Bonde G, Helverson A, et al. TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes. PLoS Genet. 2022;18:e1010207 pubmed publisher
Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nat Commun. 2021;12:5041 pubmed publisher
Ma M, Guo D, Tan Z, Du J, Guan F, Li X. Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2γ. Cancer Sci. 2021;112:3190-3204 pubmed publisher
Liu J, Liu Z, Li M, Tang W, Pratap U, Luo Y, et al. Interaction of transcription factor AP-2 gamma with proto-oncogene PELP1 promotes tumorigenesis by enhancing RET signaling. Mol Oncol. 2020;: pubmed publisher
Liu Q, Borcherding N, Shao P, Maina P, Zhang W, Qi H. Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance. EBioMedicine. 2020;51:102612 pubmed publisher
Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. 2019;179:687-702.e18 pubmed publisher
Do H, Kim D, Kang J, Son B, Seo D, Youn H, et al. TFAP2C increases cell proliferation by downregulating GADD45B and PMAIP1 in non-small cell lung cancer cells. Biol Res. 2019;52:35 pubmed publisher
Ando Y, Okeyo K, Adachi T. Modulation of adhesion microenvironment using mesh substrates triggers self-organization and primordial germ cell-like differentiation in mouse ES cells. APL Bioeng. 2019;3:016102 pubmed publisher
Chen D, Liu W, Zimmerman J, Pastor W, Kim R, Hosohama L, et al. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Rep. 2018;25:3591-3602.e5 pubmed publisher
Park J, Wu T, Cyr A, Woodfield G, de Andrade J, Spanheimer P, et al. The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis. Oncogene. 2015;34:6105-14 pubmed publisher
Jørgensen A, Young J, Nielsen J, Joensen U, Toft B, Rajpert De Meyts E, et al. Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche. Br J Cancer. 2014;110:2604-14 pubmed publisher
Spanheimer P, Askeland R, Kulak M, Wu T, Weigel R. High TFAP2C/low CD44 expression is associated with an increased rate of pathologic complete response following neoadjuvant chemotherapy in breast cancer. J Surg Res. 2013;184:519-25 pubmed publisher
Spanheimer P, Woodfield G, CYR A, Kulak M, White Baer L, Bair T, et al. Expression of the RET proto-oncogene is regulated by TFAP2C in breast cancer independent of the estrogen receptor. Ann Surg Oncol. 2013;20:2204-12 pubmed publisher
Adams C, Henke A, Gromoll J. A novel two-promoter-one-gene system of the chorionic gonadotropin ? gene enables tissue-specific expression. J Mol Endocrinol. 2011;47:285-98 pubmed publisher
Almstrup K, Lippert M, Mogensen H, Nielsen J, Hansen J, Daugaard G, et al. Screening of subfertile men for testicular carcinoma in situ by an automated image analysis-based cytological test of the ejaculate. Int J Androl. 2011;34:e21-30; discussion e30-1 pubmed publisher
Jahnukainen K, Ehmcke J, Quader M, Saiful Huq M, Epperly M, Hergenrother S, et al. Testicular recovery after irradiation differs in prepubertal and pubertal non-human primates, and can be enhanced by autologous germ cell transplantation. Hum Reprod. 2011;26:1945-54 pubmed publisher
Nielsen J, Kristensen D, Almstrup K, Jørgensen A, Olesen I, Jacobsen G, et al. A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples. Andrologia. 2012;44:78-85 pubmed publisher
Albert S, Ehmcke J, Wistuba J, Eildermann K, Behr R, Schlatt S, et al. Germ cell dynamics in the testis of the postnatal common marmoset monkey (Callithrix jacchus). Reproduction. 2010;140:733-42 pubmed publisher
Su B, Tang H, Deng M, Liao Q, Zeng X, Zhang W, et al. Stage-associated dynamic activity profile of transcription factors in nasopharyngeal carcinoma progression based on protein/DNA array analysis. OMICS. 2011;15:49-60 pubmed publisher
Salonen J, Rajpert De Meyts E, Mannisto S, Nielsen J, Graem N, Toppari J, et al. Differential developmental expression of transcription factors GATA-4 and GATA-6, their cofactor FOG-2 and downstream target genes in testicular carcinoma in situ and germ cell tumors. Eur J Endocrinol. 2010;162:625-31 pubmed publisher
Nielsen J, Lindegaard M, Friis Hansen L, Almstrup K, Leffers H, Nielsen L, et al. Lipoprotein lipase and endothelial lipase in human testis and in germ cell neoplasms. Int J Androl. 2010;33:e207-15 pubmed publisher
Salonen J, Leminen A, Stenman U, Butzow R, Heikinheimo M, Heikinheimo O. Tissue AP-2gamma and Oct-3/4, and serum CA 125 as diagnostic and prognostic markers of malignant ovarian germ cell tumors. Tumour Biol. 2008;29:50-6 pubmed publisher
Hoei Hansen C, Kraggerud S, Abeler V, Kaern J, Rajpert De Meyts E, Lothe R. Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers. Mol Cancer. 2007;6:12 pubmed
Hoei Hansen C, Carlsen E, Jorgensen N, Leffers H, Skakkebaek N, Rajpert De Meyts E. Towards a non-invasive method for early detection of testicular neoplasia in semen samples by identification of fetal germ cell-specific markers. Hum Reprod. 2007;22:167-73 pubmed
Hong S, Frierson H, Moskaluk C. AP-2gamma protein expression in intratubular germ cell neoplasia of testis. Am J Clin Pathol. 2005;124:873-7 pubmed
Hannema S, Scott I, Rajpert De Meyts E, Skakkebaek N, Coleman N, Hughes I. Testicular development in the complete androgen insensitivity syndrome. J Pathol. 2006;208:518-27 pubmed
Hoei Hansen C, Almstrup K, Nielsen J, Brask Sonne S, Graem N, Skakkebaek N, et al. Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours. Histopathology. 2005;47:48-56 pubmed
Hoei Hansen C, Rajpert De Meyts E, Carlsen E, Almstrup K, Leffers H, Skakkebaek N. A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2gamma in semen samples: case report. Hum Reprod. 2005;20:579-82 pubmed
product information
Catalog Number :
sc-12762
Product Name :
AP-2γ (6E4/4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
6E4/4
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
AP-2gamma
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA