product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ankyrin G (463) Antibody
catalog :
sc-12719
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
463
reactivity :
human, mouse, rat, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, proximity ligation assay
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 3b
Shin M, Vázquez Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón Pérez C, et al. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021;184:2715-2732.e23 pubmed publisher
  • immunohistochemistry - free floating section; human; 1:100; loading ...; fig 1s1c
Szegedi V, Paizs M, Baka J, Barzo P, Molnár G, Tamas G, et al. Robust perisomatic GABAergic self-innervation inhibits basket cells in the human and mouse supragranular neocortex. elife. 2020;9: pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 1a
Lee M, Liu Y, Chen C, Lu C, Lu S, Huang T, et al. Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. J Cell Biol. 2020;219: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 5a, s5e
  • western blot; mouse; loading ...; fig s5a
Jacko M, Weyn Vanhentenryck S, Smerdon J, Yan R, Feng H, Williams D, et al. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018;97:853-868.e6 pubmed publisher
  • western blot; mouse; loading ...; fig 5f
Kanellopoulos A, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J. 2018;37:427-445 pubmed publisher
  • proximity ligation assay; rat; 1:500; loading ...; fig 3c
  • immunocytochemistry; rat; 1:500; loading ...; fig 2b
König H, Schwamborn R, Andresen S, Kinsella S, Watters O, Fenner B, et al. NF-κB regulates neuronal ankyrin-G via a negative feedback loop. Sci Rep. 2017;7:42006 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6a
Valkova C, Liebmann L, Kramer A, Hübner C, Kaether C. The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels. Sci Rep. 2017;7:41248 pubmed publisher
  • immunocytochemistry; mouse; fig 1
Dover K, Marra C, Solinas S, Popovic M, Subramaniyam S, Zecevic D, et al. FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon. Nat Commun. 2016;7:12895 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 3
Vereczki V, Veres J, Müller K, Nagy G, Rácz B, Barsy B, et al. Synaptic Organization of Perisomatic GABAergic Inputs onto the Principal Cells of the Mouse Basolateral Amygdala. Front Neuroanat. 2016;10:20 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 2
D Este E, Kamin D, Velte C, Göttfert F, Simons M, Hell S. Subcortical cytoskeleton periodicity throughout the nervous system. Sci Rep. 2016;6:22741 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Herde M, Herbison A. Morphological Characterization of the Action Potential Initiation Segment in GnRH Neuron Dendrites and Axons of Male Mice. Endocrinology. 2015;156:4174-86 pubmed publisher
  • immunocytochemistry; rat; fig 4
Zhong G, He J, Zhou R, LORENZO D, Babcock H, Bennett V, et al. Developmental mechanism of the periodic membrane skeleton in axons. elife. 2014;3: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250
Wang X, Hooks B, Sun Q. Thorough GABAergic innervation of the entire axon initial segment revealed by an optogenetic 'laserspritzer'. J Physiol. 2014;592:4257-76 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:200
Wang X, Sun Q. Characterization of axo-axonic synapses in the piriform cortex of Mus musculus. J Comp Neurol. 2012;520:832-47 pubmed publisher
  • immunohistochemistry - free floating section; rhesus macaque; 1:200
Cruz D, Lovallo E, Stockton S, Rasband M, Lewis D. Postnatal development of synaptic structure proteins in pyramidal neuron axon initial segments in monkey prefrontal cortex. J Comp Neurol. 2009;514:353-67 pubmed publisher
Hyeon B, Lee H, Kim N, Heo W. Optogenetic dissection of RET signaling reveals robust activation of ERK and enhanced filopodia-like protrusions of regenerating axons. Mol Brain. 2023;16:56 pubmed publisher
Woo D, Seo Y, Jung H, Kim S, Kim N, Park S, et al. Locally Activating TrkB Receptor Generates Actin Waves and Specifies Axonal Fate. Cell Chem Biol. 2019;26:1652-1663.e4 pubmed publisher
Gao Y, Hisey E, Bradshaw T, Erata E, Brown W, Courtland J, et al. Plug-and-Play Protein Modification Using Homology-Independent Universal Genome Engineering. Neuron. 2019;: pubmed publisher
Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, et al. Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. Commun Biol. 2018;1: pubmed publisher
Karasmanis E, Phan C, Angelis D, Kesisova I, Hoogenraad C, McKenney R, et al. Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin. Dev Cell. 2018;46:204-218.e7 pubmed publisher
Katz E, Stoler O, Scheller A, Khrapunsky Y, Goebbels S, Kirchhoff F, et al. Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons. Proc Natl Acad Sci U S A. 2018;115:E7184-E7192 pubmed publisher
Kang Y, Lewis H, Young M, Govindaiah G, Greenfield L, Garcia Rill E, et al. Cell Type-specific Intrinsic Perithreshold Oscillations in Hippocampal GABAergic Interneurons. Neuroscience. 2018;376:80-93 pubmed publisher
Tian C, Wang K, Ke W, Guo H, Shu Y. Molecular identity of axonal sodium channels in human cortical pyramidal cells. Front Cell Neurosci. 2014;8:297 pubmed publisher
Li T, Tian C, Scalmani P, Frassoni C, Mantegazza M, Wang Y, et al. Action potential initiation in neocortical inhibitory interneurons. PLoS Biol. 2014;12:e1001944 pubmed publisher
Cijsouw T, Weber J, Broeke J, Broek J, Schut D, Kroon T, et al. Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol. 2014;204:759-75 pubmed publisher
Herde M, Iremonger K, Constantin S, Herbison A. GnRH neurons elaborate a long-range projection with shared axonal and dendritic functions. J Neurosci. 2013;33:12689-97 pubmed publisher
Massi L, Lagler M, Hartwich K, Borhegyi Z, Somogyi P, Klausberger T. Temporal dynamics of parvalbumin-expressing axo-axonic and basket cells in the rat medial prefrontal cortex in vivo. J Neurosci. 2012;32:16496-16502 pubmed publisher
Yamatani H, Kawasaki T, Mita S, Inagaki N, Hirata T. Proteomics analysis of the temporal changes in axonal proteins during maturation. Dev Neurobiol. 2010;70:523-37 pubmed publisher
Kaech S, Banker G. Culturing hippocampal neurons. Nat Protoc. 2006;1:2406-15 pubmed
product information
Catalog Number :
sc-12719
Product Name :
Ankyrin G (463) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
463
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Ankyrin G
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA