product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p53 (DO-1) HRP
catalog :
sc-126 HRP
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
HRP
clone name :
DO-1
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 4h-s
  • immunocytochemistry; human; fig 4a-f
  • western blot; human; fig 2a
De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, et al. Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation. J Pathol. 2017;242:24-38 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 2a
Qi D, Cobrinik D. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation. Oncogene. 2017;36:1760-1769 pubmed publisher
  • chromatin immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human; loading ...; fig 1d
Itahana Y, Zhang J, Göke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed publisher
  • western blot; human; loading ...; fig 1a
Shatz M, Shats I, Menendez D, Resnick M. p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways. Oncotarget. 2015;6:16963-80 pubmed
  • western blot; human; fig 2b
Zhu J, Zhao C, Zhuang T, Jonsson P, Sinha I, Williams C, et al. RING finger protein 31 promotes p53 degradation in breast cancer cells. Oncogene. 2016;35:1955-64 pubmed publisher
  • western blot; human; fig 6
Butin Israeli V, Adam S, Jain N, Otte G, Neems D, Wiesmüller L, et al. Role of lamin b1 in chromatin instability. Mol Cell Biol. 2015;35:884-98 pubmed publisher
Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
Du W, Jiang P, Mancuso A, Stonestrom A, Brewer M, Minn A, et al. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol. 2013;15:991-1000 pubmed publisher
Yang H, Zhang W, Pan H, Feldser H, Lainez E, Miller C, et al. SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-?B activity. PLoS ONE. 2012;7:e46364 pubmed publisher
Lee J, Kang S, Jeon Y, Park J, You J, Ha S, et al. Protein L-isoaspartyl methyltransferase regulates p53 activity. Nat Commun. 2012;3:927 pubmed publisher
Navaraj A, Finnberg N, Dicker D, Yang W, Matthew E, El Deiry W. Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-Ras. Cancer Biol Ther. 2009;8:2417-44 pubmed
Radhakrishnan S, Bhat U, Halasi M, Gartel A. P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents. Oncogene. 2008;27:1306-9 pubmed
Radhakrishnan S, Gartel A. CDK9 phosphorylates p53 on serine residues 33, 315 and 392. Cell Cycle. 2006;5:519-21 pubmed
Radhakrishnan S, Gierut J, Gartel A. Multiple alternate p21 transcripts are regulated by p53 in human cells. Oncogene. 2006;25:1812-5 pubmed
product information
Catalog Number :
sc-126 HRP
Product Name :
p53 (DO-1) HRP
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
horseradish peroxidase
Clone Name :
DO-1
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
p53
Specificity :
mouse, rat, human
Uses :
WB, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA