Shen M, Zhang R, Jia W, Zhu Z, Zhao L, Huang G, et al. RNA-binding protein p54nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer. Cell Death Dis. 2022;13:42 pubmed publisher

Wang Z, Goto Y, Allevato M, Wu V, Saddawi Konefka R, Gilardi M, et al. Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Nat Commun. 2021;12:2383 pubmed publisher

Chew H, De Lima P, Gonzalez Cruz J, Banushi B, Echejoh G, Hu L, et al. Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell. 2020;180:895-914.e27 pubmed publisher

Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J. N-Glycosylation of integrin ?5 acts as a switch for EGFR-mediated complex formation of integrin ?5?1 to ?6?4. Sci Rep. 2016;6:33507 pubmed publisher

Kimani S, Kumar S, Davra V, Chang Y, Kasikara C, Geng K, et al. Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. Cell Commun Signal. 2016;14:19 pubmed publisher

He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed publisher

Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, et al. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. Oncotarget. 2015;6:29209-23 pubmed publisher

Wu Y, Deng W, Klinke D. Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers. Analyst. 2015;140:6631-42 pubmed publisher

Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed publisher

Young O, Tang Z, Niven Fairchild T, Tadesse S, Krikun G, Norwitz E, et al. Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. Am J Reprod Immunol. 2015;73:22-35 pubmed publisher

Hamdollah Zadeh M, Amin E, Hoareau Aveilla C, Domingo E, Symonds K, Ye X, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Mol Oncol. 2015;9:167-78 pubmed publisher

Zhang X, Zhang H, Tighiouart M, Lee J, Shin H, Khuri F, et al. Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor. Int J Cancer. 2008;123:1005-14 pubmed publisher

Wang P, Zhou R, Zhou R, Feng S, Zhao L, Li W, et al. Epidermal growth factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium. Redox Biol. 2024;69:102976 pubmed publisher

Melo V, Nelemans L, Vlaming M, Lourens H, Wiersma V, Bilemjian V, et al. EGFR-selective activation of CD27 co-stimulatory signaling by a bispecific antibody enhances anti-tumor activity of T cells. Front Immunol. 2023;14:1191866 pubmed publisher

Sabino C, Bender D, Herrlein M, Hildt E. The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro. J Virol. 2021;95:e0119521 pubmed publisher

Ahearn I, Court H, Siddiqui F, Abankwa D, Philips M. NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane. Life Sci Alliance. 2021;4: pubmed publisher

Jones S, King P, Antonescu C, Sugiyama M, Bhamra A, Surinova S, et al. Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation. Sci Rep. 2020;10:663 pubmed publisher

Chen M, Choi S, Jung O, Wen T, Baum C, Thapa N, et al. The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif. Sci Rep. 2019;9:9126 pubmed publisher

Rivero Ríos P, Romo Lozano M, Madero Pérez J, Thomas A, Biosa A, Greggio E, et al. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A. J Biol Chem. 2019;294:4738-4758 pubmed publisher

de Beer M, Kuipers J, van Bergen en Henegouwen P, Giepmans B. A small protein probe for correlated microscopy of endogenous proteins. Histochem Cell Biol. 2018;149:261-268 pubmed publisher

Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher

Ortiz Zapater E, Lee R, Owen W, Weitsman G, Fruhwirth G, Dunn R, et al. MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition. PLoS ONE. 2017;12:e0170798 pubmed publisher

Chamberland J, Antonow L, Dias Santos M, Ritter B. NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. J Cell Sci. 2016;129:2625-37 pubmed publisher

Dinish U, Balasundaram G, Chang Y, Olivo M. Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags. Sci Rep. 2014;4:4075 pubmed publisher

Stoczyńska Fidelus E, Piaskowski S, Bienkowski M, Banaszczyk M, Hulas Bigoszewska K, Winiecka Klimek M, et al. The failure in the stabilization of glioblastoma-derived cell lines: spontaneous in vitro senescence as the main culprit. PLoS ONE. 2014;9:e87136 pubmed publisher

Konkel M, Samuelson D, Eucker T, Shelden E, O Loughlin J. Invasion of epithelial cells by Campylobacter jejuni is independent of caveolae. Cell Commun Signal. 2013;11:100 pubmed publisher

Leroy M, Perroud J, Darbellay B, Bernheim L, Konig S. Epidermal growth factor receptor down-regulation triggers human myoblast differentiation. PLoS ONE. 2013;8:e71770 pubmed publisher

Wolf Goldberg T, Barbul A, Ben Dov N, Korenstein R. Low electric fields induce ligand-independent activation of EGF receptor and ERK via electrochemical elevation of H(+) and ROS concentrations. Biochim Biophys Acta. 2013;1833:1396-408 pubmed publisher

Moretti J, Chastagner P, Liang C, Cohn M, Israel A, Brou C. The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation. J Biol Chem. 2012;287:29429-41 pubmed publisher

Pan S, Chen R, Brand R, Hawley S, Tamura Y, Gafken P, et al. Multiplex targeted proteomic assay for biomarker detection in plasma: a pancreatic cancer biomarker case study. J Proteome Res. 2012;11:1937-48 pubmed publisher

U S D, Fu C, Soh K, Ramaswamy B, Kumar A, Olivo M. Highly sensitive SERS detection of cancer proteins in low sample volume using hollow core photonic crystal fiber. Biosens Bioelectron. 2012;33:293-8 pubmed publisher

Wilson K, Mill C, Gallo R, Cameron E, VanBrocklin H, Settleman J, et al. The Q43L mutant of neuregulin 2? is a pan-ErbB receptor antagonist. Biochem J. 2012;443:133-44 pubmed publisher

Sekiyama A, Gon Y, Terakado M, Takeshita I, Kozu Y, Maruoka S, et al. Glucocorticoids enhance airway epithelial barrier integrity. Int Immunopharmacol. 2012;12:350-7 pubmed publisher

McWilliam I, Chong Kwan M, Hall D. Inkjet printing for the production of protein microarrays. Methods Mol Biol. 2011;785:345-61 pubmed publisher

Takahashi Y, Miyamoto T, Shiku H, Ino K, Yasukawa T, Asano R, et al. Electrochemical detection of receptor-mediated endocytosis by scanning electrochemical microscopy. Phys Chem Chem Phys. 2011;13:16569-73 pubmed publisher

Gon Y, Matsumoto K, Terakado M, Sekiyama A, Maruoka S, Takeshita I, et al. Heregulin activation of ErbB2/ErbB3 signaling potentiates the integrity of airway epithelial barrier. Exp Cell Res. 2011;317:1947-53 pubmed publisher

Hara T, Miyazaki M, Hakuno F, Takahashi S, Chida K. PKC? promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions. Cell Death Dis. 2011;2:e157 pubmed publisher

Kormos B, Belso N, Bebes A, Szabad G, Bacsa S, Szell M, et al. In vitro dedifferentiation of melanocytes from adult epidermis. PLoS ONE. 2011;6:e17197 pubmed publisher

Licitra L, Perrone F, Tamborini E, Bertola L, Ghirelli C, Negri T, et al. Role of EGFR family receptors in proliferation of squamous carcinoma cells induced by wound healing fluids of head and neck cancer patients. Ann Oncol. 2011;22:1886-93 pubmed publisher

Bertelsen V, Sak M, Breen K, Rødland M, Johannessen L, Traub L, et al. A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner. Traffic. 2011;12:507-20 pubmed publisher

Mill C, Gettinger K, Riese D. Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines. Exp Cell Res. 2011;317:392-404 pubmed publisher

Tasaki S, Nagasaki M, Kozuka Hata H, Semba K, Gotoh N, Hattori S, et al. Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. PLoS ONE. 2010;5:e13926 pubmed publisher

Gupta P, Han S, Holgado Madruga M, Mitra S, Li G, Nitta R, et al. Development of an EGFRvIII specific recombinant antibody. BMC Biotechnol. 2010;10:72 pubmed publisher

Maiti K, Dinish U, Fu C, Lee J, Soh K, Yun S, et al. Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection. Biosens Bioelectron. 2010;26:398-403 pubmed publisher

Tamborini E, Virdis E, Negri T, Orsenigo M, Brich S, Conca E, et al. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol. 2010;12:776-89 pubmed publisher

Nencioni A, Cea M, Garuti A, Passalacqua M, Raffaghello L, Soncini D, et al. Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression. PLoS ONE. 2010;5:e9024 pubmed publisher

Visser Smit G, Place T, Cole S, Clausen K, Vemuganti S, Zhang G, et al. Cbl controls EGFR fate by regulating early endosome fusion. Sci Signal. 2009;2:ra86 pubmed publisher

Swartling F, Ferletta M, Kastemar M, Weiss W, Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene. 2009;28:3121-31 pubmed publisher

Takahashi Y, Miyamoto T, Shiku H, Asano R, Yasukawa T, Kumagai I, et al. Electrochemical detection of epidermal growth factor receptors on a single living cell surface by scanning electrochemical microscopy. Anal Chem. 2009;81:2785-90 pubmed publisher

Perrone F, Da Riva L, Orsenigo M, Losa M, Jocollè G, Millefanti C, et al. PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor. Neuro Oncol. 2009;11:725-36 pubmed publisher

Rawlins J, Fernandez C, Cozby M, Opperman L. Timing of Egf treatment differentially affects Tgf-beta2 induced cranial suture closure. Exp Biol Med (Maywood). 2008;233:1518-26 pubmed publisher

Bergin D, Greene C, Sterchi E, Kenna C, Geraghty P, Belaaouaj A, et al. Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. J Biol Chem. 2008;283:31736-44 pubmed publisher

Liu Y, Wang B, Wang J, Wan W, Sun R, Zhao Y, et al. Down-regulation of PKCzeta expression inhibits chemotaxis signal transduction in human lung cancer cells. Lung Cancer. 2009;63:210-8 pubmed publisher

Chastagner P, Israel A, Brou C. AIP4/Itch regulates Notch receptor degradation in the absence of ligand. PLoS ONE. 2008;3:e2735 pubmed publisher

Quinchia Rios B, Guerrero M, Abozeid S, Bainbridge B, Darveau R, Compton T, et al. Down-regulation of epidermal growth factor receptor-dependent signaling by Porphyromonas gingivalis lipopolysaccharide in life-expanded human gingival fibroblasts. J Periodontal Res. 2008;43:290-304 pubmed publisher

Szabad G, Kormos B, Pivarcsi A, Szell M, Kis K, Kenderessy Szabo A, et al. Human adult epidermal melanocytes cultured without chemical mitogens express the EGF receptor and respond to EGF. Arch Dermatol Res. 2007;299:191-200 pubmed

Melendez K, Wallen E, Edwards B, Mobarak C, Bear D, Moseley P. Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells. Cell Stress Chaperones. 2006;11:334-42 pubmed

Rajput A, Koterba A, Kreisberg J, Foster J, Willson J, Brattain M. A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo. Cancer Res. 2007;67:665-73 pubmed

Kim B, Olzmann J, Barsh G, Chin L, Li L. Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Mol Biol Cell. 2007;18:1129-42 pubmed

Ning Y, Buranda T, Hudson L. Activated epidermal growth factor receptor induces integrin alpha2 internalization via caveolae/raft-dependent endocytic pathway. J Biol Chem. 2007;282:6380-7 pubmed

Zhang Y, Jiang Y, Geiser V, Zhou J, Jones C. Bovine herpesvirus 1 immediate-early protein (bICP0) interacts with the histone acetyltransferase p300, which stimulates productive infection and gC promoter activity. J Gen Virol. 2006;87:1843-51 pubmed publisher

McIntire R, Petroff M, Phillips T, Hunt J. In vitro models for studying human uterine and placental macrophages. Methods Mol Med. 2006;122:123-48 pubmed

Sun X, Gemzell Danielsson K, Li H, Ståbi B, Stavreus Evers A. Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone. Fertil Steril. 2006;85:171-8 pubmed

Johannessen L, Pedersen N, Pedersen K, Madshus I, Stang E. Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. Mol Cell Biol. 2006;26:389-401 pubmed

Semino C, Kamm R, Lauffenburger D. Autocrine EGF receptor activation mediates endothelial cell migration and vascular morphogenesis induced by VEGF under interstitial flow. Exp Cell Res. 2006;312:289-98 pubmed

Takai N, Jain A, Kawamata N, Popoviciu L, Said J, Whittaker S, et al. 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth. Cancer. 2005;104:2701-8 pubmed

Van Schaeybroeck S, Karaiskou McCaul A, Kelly D, Longley D, Galligan L, Van Cutsem E, et al. Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy. Clin Cancer Res. 2005;11:7480-9 pubmed

Augoff K, Taboła R, Kula J, Gosk J, Rutowski R. Epidermal growth factor receptor (EGF-R) in Dupuytren's disease. J Hand Surg Br. 2005;30:570-3 pubmed

Amin D, Tuck D, Stern D. Neuregulin-regulated gene expression in mammary carcinoma cells. Exp Cell Res. 2005;309:12-23 pubmed

Wedge S, Kendrew J, Hennequin L, Valentine P, Barry S, Brave S, et al. AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res. 2005;65:4389-400 pubmed

Zhang B, Srirangam A, Potter D, Roman A. HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes. Oncogene. 2005;24:2585-8 pubmed

Spengeman J, Green T, McCubrey J, Bertrand F. Activated EGFR promotes the survival of B-lineage acute leukemia in the absence of stromal cells. Cell Cycle. 2005;4:483-7 pubmed

Aifa S, Aydin J, Nordvall G, Lundstrom I, Svensson S, Hermanson O. A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. Exp Cell Res. 2005;302:108-14 pubmed

Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, et al. Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol. 2003;161:197-209 pubmed

Mariotti A, Kedeshian P, Dans M, Curatola A, Gagnoux Palacios L, Giancotti F. EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol. 2001;155:447-58 pubmed