product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
EGFR (R-1) Antibody
catalog :
sc-101
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
R-1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s4b
  • western blot; human; loading ...; fig 5a
Solis N, Swidergall M, Bruno V, Gaffen S, Filler S. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. MBio. 2017;8: pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig 1a
Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, et al. The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR. J Cell Biol. 2016;215:543-558 pubmed
  • immunocytochemistry; human; 1:100
Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed publisher
  • western blot; human; fig 1
Ponti D, Bastianelli D, Rosa P, Pacini L, Ibrahim M, Rendina E, et al. The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions. BMC Cell Biol. 2015;16:27 pubmed publisher
  • immunocytochemistry; human; fig 3
Valley C, Arndt Jovin D, Karedla N, Steinkamp M, Chizhik A, Hlavacek W, et al. Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer. Mol Biol Cell. 2015;26:4087-99 pubmed publisher
  • immunoprecipitation; human; fig 5
  • immunocytochemistry; human; fig s3
Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed publisher
  • immunohistochemistry; rat; 1:200
Gowing G, Shelley B, Staggenborg K, Hurley A, Avalos P, Victoroff J, et al. Glial cell line-derived neurotrophic factor-secreting human neural progenitors show long-term survival, maturation into astrocytes, and no tumor formation following transplantation into the spinal cord of immunocompromised rats. Neuroreport. 2014;25:367-72 pubmed publisher
Wang J, Lau P, Li C, Guo Y. The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR). J Biol Chem. 2023;299:102979 pubmed publisher
Deygas M, Gadet R, Gillet G, Rimokh R, Gonzalo P, Mikaelian I. Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen. Nat Commun. 2018;9:4545 pubmed publisher
Currier M, Lee S, Stobart C, Hotard A, Villenave R, Meng J, et al. EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression. PLoS Pathog. 2016;12:e1005622 pubmed publisher
Kortüm F, Harms F, Hennighausen N, Rosenberger G. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor. PLoS ONE. 2015;10:e0132737 pubmed publisher
Valley C, Liu S, Lidke D, Lidke K. Sequential superresolution imaging of multiple targets using a single fluorophore. PLoS ONE. 2015;10:e0123941 pubmed publisher
Nodale C, Vescarelli E, D Amici S, Maffucci D, Ceccarelli S, Monti M, et al. Characterization of human vaginal mucosa cells for autologous in vitro cultured vaginal tissue transplantation in patients with MRKH syndrome. Biomed Res Int. 2014;2014:201518 pubmed publisher
Ponti D, Bellenchi G, Puca R, Bastianelli D, Maroder M, Ragona G, et al. The transcription factor EGR1 localizes to the nucleolus and is linked to suppression of ribosomal precursor synthesis. PLoS ONE. 2014;9:e96037 pubmed publisher
Siegemund M, Pollak N, Seifert O, Wahl K, Hanak K, Vogel A, et al. Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity. Cell Death Dis. 2012;3:e295 pubmed publisher
Li J, Li Y, Feng Z, Chen X. Anti-tumor activity of a novel EGFR tyrosine kinase inhibitor against human NSCLC in vitro and in vivo. Cancer Lett. 2009;279:213-20 pubmed publisher
Li J, Meng Y, Liu Y, Feng Z, Chen X. F84, a quinazoline derivative, exhibits high potent antitumor activity against human gynecologic malignancies. Invest New Drugs. 2010;28:132-8 pubmed publisher
Watt H, Kharmate G, Kumar U. Somatostatin receptors 1 and 5 heterodimerize with epidermal growth factor receptor: agonist-dependent modulation of the downstream MAPK signalling pathway in breast cancer cells. Cell Signal. 2009;21:428-39 pubmed publisher
Kruser T, Armstrong E, Ghia A, Huang S, Wheeler D, Radinsky R, et al. Augmentation of radiation response by panitumumab in models of upper aerodigestive tract cancer. Int J Radiat Oncol Biol Phys. 2008;72:534-42 pubmed publisher
Kimura H, Sakai K, Arao T, Shimoyama T, Tamura T, Nishio K. Antibody-dependent cellular cytotoxicity of cetuximab against tumor cells with wild-type or mutant epidermal growth factor receptor. Cancer Sci. 2007;98:1275-80 pubmed
Kleiner S, Faisal A, Nagamine Y. Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling. FEBS J. 2007;274:227-40 pubmed
Visram H, Greer P. 17beta-estradiol and tamoxifen stimulate rapid and transient ERK activationin MCF-7 cells via distinct signaling mechanisms. Cancer Biol Ther. 2006;5:1677-82 pubmed
product information
Catalog Number :
sc-101
Product Name :
EGFR (R-1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
R-1
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
EGFR
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, FCM
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA