product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p53 (Pab 246) Antibody
catalog :
sc-100
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Pab 246
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 24
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human
  • western blot; human
Tomicic M, Aasland D, Naumann S, Meise R, Barckhausen C, Kaina B, et al. Translesion polymerase ? is upregulated by cancer therapeutics and confers anticancer drug resistance. Cancer Res. 2014;74:5585-96 pubmed publisher
  • chromatin immunoprecipitation; human
Bungard D, Fuerth B, Zeng P, Faubert B, Maas N, Viollet B, et al. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science. 2010;329:1201-5 pubmed publisher
Walther S, Strittmatter F, Roosen A, Heinzer F, Rutz B, Stief C, et al. Expression and alpha1-adrenoceptor regulation of caldesmon in human prostate smooth muscle. Urology. 2012;79:745.e5-12 pubmed publisher
Xiang Y, Xu J, Li L, Lin X, Chen X, Zhang X, et al. Calorie restriction increases primordial follicle reserve in mature female chemotherapy-treated rats. Gene. 2012;493:77-82 pubmed publisher
Sheng R, Gu Z, Xie M. Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy. Int J Cardiol. 2013;162:199-209 pubmed publisher
Weis E, Schoen H, Victor A, Spix C, Ludwig M, Schneider Raetzke B, et al. Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer. PLoS ONE. 2011;6:e25750 pubmed publisher
Camboni M, Hammond S, Martin L, Martin P. Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient mice. J Pathol. 2012;226:40-9 pubmed publisher
Li B, Reddy S, Comai L. Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells. Aging (Albany NY). 2011;3:395-406 pubmed
Tomicic M, Reischmann P, Rasenberger B, Meise R, Kaina B, Christmann M. Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity. Cell Mol Life Sci. 2011;68:1785-98 pubmed publisher
Sheng R, Gu Z, Xie M, Zhou W, Guo C. Epigallocatechin gallate protects H9c2 cardiomyoblasts against hydrogen dioxides- induced apoptosis and telomere attrition. Eur J Pharmacol. 2010;641:199-206 pubmed publisher
Quintavalle M, Elia L, Condorelli G, Courtneidge S. MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J Cell Biol. 2010;189:13-22 pubmed publisher
Robinson J, Yu X, Hong S, Zhou C, Kim N, DeMasi D, et al. Embryonic toxicokinetic and dynamic differences underlying strain sensitivity to cadmium during neurulation. Reprod Toxicol. 2010;29:279-85 pubmed publisher
Han W, Liu G. EGR-1 decoy ODNs inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia of balloon-injured arteries in rat. Life Sci. 2010;86:234-43 pubmed publisher
Shen X, Do H, Li Y, Chung W, Tomasz M, de Winter J, et al. Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell. 2009;35:716-23 pubmed publisher
Jiang J, Chan Y, Loh Y, Cai J, Tong G, Lim C, et al. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol. 2008;10:353-60 pubmed publisher
Li B, Jog S, Reddy S, Comai L. WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening. Mol Cell Biol. 2008;28:1892-904 pubmed publisher
Raymond K, Kreft M, Song J, Janssen H, Sonnenberg A. Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function. Mol Biol Cell. 2007;18:4210-21 pubmed
Sheng R, Gu Z, Xie M, Zhou W, Guo C. EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats. Acta Pharmacol Sin. 2007;28:191-201 pubmed
Benitez D, Pozo Guisado E, Alvarez Barrientos A, Fernandez Salguero P, Castellon E. Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines. J Androl. 2007;28:282-93 pubmed
Chauhan M, Yallampalli U, Reed L, Yallampalli C. Adrenomedullin 2 antagonist infusion to rats during midgestation causes fetoplacental growth restriction through apoptosis. Biol Reprod. 2006;75:940-7 pubmed
Nannenga B, Lu X, Dumble M, van Maanen M, Nguyen T, Sutton R, et al. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Mol Carcinog. 2006;45:594-604 pubmed
Piltti K, Kerosuo L, Hakanen J, Eriksson M, Angers Loustau A, Leppa S, et al. E6/E7 oncogenes increase and tumor suppressors decrease the proportion of self-renewing neural progenitor cells. Oncogene. 2006;25:4880-9 pubmed
Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L, et al. C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution. Development. 2005;132:4675-85 pubmed
Raymond K, Kreft M, Janssen H, Calafat J, Sonnenberg A. Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice. J Cell Sci. 2005;118:1045-60 pubmed
product information
Catalog Number :
sc-100
Product Name :
p53 (Pab 246) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
Pab 246
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
p53
Specificity :
mouse, rat
Uses :
WB, IP, IF
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA