product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
insulin Rβ (29B4) Antibody
catalog :
sc-09
quantity :
100 µg/ml
price :
333 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29B4
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100; fig 2
Stouffer M, Woods C, Patel J, Lee C, Witkovsky P, Bao L, et al. Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward. Nat Commun. 2015;6:8543 pubmed publisher
  • western blot; human; 1:1000
Kim E, Kim S, Jin X, Ham S, Kim J, Park J, et al. Epidermal growth factor receptor variant III renders glioma cancer cells less differentiated by JAGGED1. Tumour Biol. 2015;36:2921-8 pubmed publisher
  • western blot; African green monkey
Wu J, Guidotti G. Construction and characterization of a monomeric insulin receptor. J Biol Chem. 2002;277:27809-17 pubmed
Lecosnier S, Cordier C, Simon P, Francois J, Saison Behmoaras T. A steric blocker of translation elongation inhibits IGF-1R expression and cell transformation. FASEB J. 2011;25:2201-10 pubmed publisher
Saiya Cork K, Collins R, Parkin B, Ouillette P, Kuizon E, Kujawski L, et al. A pathobiological role of the insulin receptor in chronic lymphocytic leukemia. Clin Cancer Res. 2011;17:2679-92 pubmed publisher
Dinchuk J, Cao C, Huang F, Reeves K, Wang J, Myers F, et al. Insulin receptor (IR) pathway hyperactivity in IGF-IR null cells and suppression of downstream growth signaling using the dual IGF-IR/IR inhibitor, BMS-754807. Endocrinology. 2010;151:4123-32 pubmed publisher
Nieto Vazquez I, Fernández Veledo S, de Alvaro C, Lorenzo M. Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle. Diabetes. 2008;57:3211-21 pubmed publisher
Fernández Veledo S, Nieto Vazquez I, de Castro J, Ramos M, Brüderlein S, Moller P, et al. Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes. J Clin Endocrinol Metab. 2008;93:2866-76 pubmed publisher
Nieto Vazquez I, Fernández Veledo S, de Alvaro C, Rondinone C, Valverde A, Lorenzo M. Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance. Diabetes. 2007;56:404-13 pubmed
Fernandez Veledo S, Nieto Vazquez I, Rondinone C, Lorenzo M. Liver X receptor agonists ameliorate TNFalpha-induced insulin resistance in murine brown adipocytes by downregulating protein tyrosine phosphatase-1B gene expression. Diabetologia. 2006;49:3038-48 pubmed
Tang X, Powelka A, Soriano N, Czech M, Guilherme A. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes. J Biol Chem. 2005;280:22523-9 pubmed
product information
Catalog Number :
sc-09
Product Name :
insulin Rβ (29B4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
29B4
Isotype :
IgG1
Size :
100 µg/ml
List Price :
333 USD
Immunogen :
insulin Rbeta
Specificity :
mouse, rat, human
Uses :
WB, IP, KA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA