product summary
company name :
SWant
product type :
antibody
product name :
Na+-Ca2+ exchanger protein (cardiac)
catalog :
R3F1
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse, rat, sheep
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 1
Wang Y, Chen L, Li M, Cha H, Iwamoto T, Zhang J. Conditional knockout of smooth muscle sodium calcium exchanger type-1 lowers blood pressure and attenuates Angiotensin II-salt hypertension. Physiol Rep. 2015;3: pubmed publisher
  • immunohistochemistry - frozen section; sheep; 1:200; loading ...; fig 4
Munro M, Soeller C. Early transverse tubule development begins in utero in the sheep heart. J Muscle Res Cell Motil. 2017;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Munro M, Jayasinghe I, Wang Q, Quick A, Wang W, Baddeley D, et al. Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes. J Cell Sci. 2016;129:4388-4398 pubmed
  • immunohistochemistry; rat; 1:100
Hou Y, Jayasinghe I, Crossman D, Baddeley D, Soeller C. Nanoscale analysis of ryanodine receptor clusters in dyadic couplings of rat cardiac myocytes. J Mol Cell Cardiol. 2015;80:45-55 pubmed publisher
  • western blot; rat; fig 2
Zhang H, Cannell M, Kim S, Watson J, Norman R, Calaghan S, et al. Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload. PLoS ONE. 2015;10:e0144309 pubmed publisher
  • immunocytochemistry; mouse; 1:200; tbl 1
Liu J, Xin L, Benson V, Allen D, Ju Y. Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells. Front Physiol. 2015;6:69 pubmed publisher
  • western blot; mouse; fig 6
Dweck D, Sanchez-Gonzalez M, Chang A, Dulce R, Badger C, Koutnik A, et al. Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy. J Biol Chem. 2014;289:23097-111 pubmed publisher
  • immunocytochemistry; rat; 1:500
Ho W, Davis A, Chadha P, Greenwood I. Effective contractile response to voltage-gated Na+ channels revealed by a channel activator. Am J Physiol Cell Physiol. 2013;304:C739-47 pubmed publisher
  • western blot; mouse; 1:1000
Chiang D, Kongchan N, Beavers D, Alsina K, Voigt N, Neilson J, et al. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014;7:1214-22 pubmed publisher
Hamlyn J, Linde C, Gao J, Huang B, Golovina V, Blaustein M, et al. Neuroendocrine humoral and vascular components in the pressor pathway for brain angiotensin II: a new axis in long term blood pressure control. PLoS ONE. 2014;9:e108916 pubmed publisher
Fares E, Pyle W, Ray G, Rose R, Denovan-Wright E, Chen R, et al. The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart. PLoS ONE. 2013;8:e74719 pubmed publisher
Magi S, Lariccia V, Castaldo P, Arcangeli S, Nasti A, Giordano A, et al. Physical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondria. PLoS ONE. 2012;7:e34015 pubmed publisher
Qayyum F, Al-Bondokji I, Kuszczak I, Samson S, Grover A. Sodium-calcium exchange mediated contraction in left anterior descending and left ventricular branch arteries. J Cell Mol Med. 2009;13:3742-52 pubmed publisher
Burr A, Millay D, Goonasekera S, Park K, Sargent M, Collins J, et al. Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Mol Cell Biol. 2014;34:1991-2002 pubmed publisher
Hamming K, Soliman D, Webster N, Searle G, Matemisz L, Liknes D, et al. Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion. Diabetes. 2010;59:1686-93 pubmed publisher
Szewczyk M, Davis K, Samson S, Simpson F, Rangachari P, Grover A. Ca2+-pumps and Na2+-Ca2+-exchangers in coronary artery endothelium versus smooth muscle. J Cell Mol Med. 2007;11:129-38 pubmed
product information
Product :
Na+-Ca2+ exchanger protein (cardiac)
Number :
R3F1
Host animal :
Mouse monoclonal, IgG1
Antibody form :
Conc. Supernat lyophil.
Qty :
200 µl
Price US$ :
380
more info or order :
company information
SWant
P.O.Box 327 CH-1723 Marly 1
info@swant.com
www.swant.com
headquarters: Switzerland