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company name :
SCICONS
product name :
anti-dsRNA mAb K1
catalog :
10020200
quantity :
200 ug
price :
375 USD
more info or order :
citations: 49
Reference
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Kreit M, Vertommen D, Gillet L, Michiels T. The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. PLoS ONE. 2015;10:e0133190 pubmed publisher
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Uchida L, Espada Murao L, Takamatsu Y, Okamoto K, Hayasaka D, Yu F, et al. The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response. Sci Rep. 2014;4:7395 pubmed publisher
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Kawashima T, Kosaka A, Yan H, Guo Z, Uchiyama R, Fukui R, et al. Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-?. Immunity. 2013;38:1187-97 pubmed publisher
Hayashi Y, Onomoto K, Narita R, Yoneyama M, Kato H, Nakagawa T, et al. Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium. Microbes Infect. 2013;15:592-8 pubmed publisher
Short J, Nakayinga R, Hughes G, Walter C, Dorrington R. Providence virus (family: Carmotetraviridae) replicates vRNA in association with the Golgi apparatus and secretory vesicles. J Gen Virol. 2013;94:1073-8 pubmed publisher
Voss A, Bode G, Kerkhoff C. Double-stranded RNA induces IL-8 and MCP-1 gene expression via TLR3 in HaCaT-keratinocytes. Inflamm Allergy Drug Targets. 2012;11:397-405 pubmed
Clavarino G, Cláudio N, Couderc T, Dalet A, Judith D, Camosseto V, et al. Induction of GADD34 is necessary for dsRNA-dependent interferon-? production and participates in the control of Chikungunya virus infection. PLoS Pathog. 2012;8:e1002708 pubmed publisher
Hagemeijer M, Vonk A, Monastyrska I, Rottier P, de Haan C. Visualizing coronavirus RNA synthesis in time by using click chemistry. J Virol. 2012;86:5808-16 pubmed publisher
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product information
Catalog Number :
10020200
Product Name :
anti-dsRNA mAb K1
Product Type :
antibody
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
K1
Isotype :
IgG2a
Light Chain :
kappa
Size :
200 ug
List Price :
375 USD
Image Legend :
K1 antibody is used to detect dsRNA in MEFs treated with poly I:C (lower panel). Presence of dsRNA is concomitant with phosphorylation of eIF2a and thus protein synthesis arrest (upper panel). Figure taken from Clavarino et al.(2012) PLoS Pathog 8:e1002708. PubMed ID 22615568
Product Description :
anti-dsRNA mAb K1
CrossReactivity :
none known
SpeciesSummary :
all known living organisms
Background :
depends on organism / fixation
Immunogen :
dsRNA
Epitope :
dsRNA
Localization :
depends on organism / physiological state / viral infection
Specificity :
dsRNA
Purity :
pure, affinity purified protein A
Buffer :
PBS
Packaging :
glass ampoule in protective box
Concentration :
lyophilised, 1 mg/ml after reconstitution
Uses :
Immunofluorescence, immunehistology, immune electronmicroscopy, immunoblotting, immunprecipitation, ELISA
Application Summary :
multipurpose
Storage :
transport at ambient temperature, -20 Celsius for long term storage
more info or order :
company information
SCICONS
Hosok tere 2, 3044 Szirak
info@scicons.eu
scicons.eu
36/1/951-6420
headquarters: Hungary