product summary
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company name :
SCICONS
product type :
antibody
product name :
anti dsRNA mAb J2
catalog :
10010200
quantity :
200 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
J2
reactivity :
SARS coronavirus
application :
immunohistochemistry
more info or order :
citations: 456
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; SARS coronavirus; 1:200; loading ...; fig 3b
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Morel K, Sheahan A, Burkhart D, Baca S, Boufaied N, Liu Y, et al. EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nat Cancer. 2021;2:444-456 pubmed publisher
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Nguyen T, Smith B, Tate M, Belz G, Barrios M, Elgass K, et al. SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition. Immunity. 2017;47:498-509.e6 pubmed publisher
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Poynter S, Dewitte Orr S. Visualizing Virus-Derived dsRNA Using Antibody-Independent and -Dependent Methods. Methods Mol Biol. 2017;1656:103-118 pubmed publisher
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Monjo A, Poynter S, Dewitte Orr S. CHSE-214: A model for studying extracellular dsRNA sensing in vitro. Fish Shellfish Immunol. 2017;68:266-271 pubmed publisher
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Zhang X, Wang T, Dai X, Zhang Y, Jiang H, Zhang Q, et al. Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion. Biochem Biophys Res Commun. 2016;479:683-689 pubmed publisher
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Conzemius R, Ganjian H, Blaas D, Fuchs R. ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments. J Virol. 2016;90:7934-42 pubmed publisher
Liu R, Moss B. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants. J Virol. 2016;90:7864-79 pubmed publisher
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Kim C, Kang H, Kim D, Song J, Choi M, Kang M, et al. Antiviral activity of micafungin against enterovirus 71. Virol J. 2016;13:99 pubmed publisher
Tsai T, Chen C, Lin Y, Chang C, Tsai C, Cheng Y, et al. Microglia retard dengue virus-induced acute viral encephalitis. Sci Rep. 2016;6:27670 pubmed publisher
Maier H, Neuman B, Bickerton E, Keep S, Alrashedi H, Hall R, et al. Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity. Sci Rep. 2016;6:27126 pubmed publisher
Vázquez Calvo A, Caridi F, González Magaldi M, Saiz J, Sobrino F, Martín Acebes M. The Amino Acid Substitution Q65H in the 2C Protein of Swine Vesicular Disease Virus Confers Resistance to Golgi Disrupting Drugs. Front Microbiol. 2016;7:612 pubmed publisher
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product information
Catalog Number :
10010200
Product Name :
anti-dsRNA mAb J2
Web URL Link :
www.scicons.eu
Product Type :
antibody
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
J2
Isotype :
IgG2a
Light Chain :
kappa
Size :
200 ug
Image Legend :
Immunofluorescence microscopy using J2 antibody reveals dsRNA (labelled in red), a marker for the the viral replication complex, in HuH-7 cells infected with Dengue virus. Cellular DNA is labelled with DAPI (blue). Figure taken from Anwar et al. (2011) PLoS One 6:e23246. Pubmed ID 21858043
Product Description :
anti-dsRNA mAb J2
CrossReactivity :
none known
SpeciesSummary :
all known living organisms
Background :
depends on organism / fixation
ALTnames :
J2
Immunogen :
dsRNA
Epitope :
dsRNA
Localization :
depends on organism / physiological state / viral infection
Specificity :
dsRNA
Purity :
pure, affinity purified protein A
Buffer :
PBS
Packaging :
glass ampoule in protective box
Concentration :
lyophilised, 1 mg/ml after reconstitution
Uses :
Immunofluorescence, immunehistology, immune electronmicroscopy, immunoblotting, immunprecipitation, ELISA
Application Summary :
multipurpose
Storage :
transport at ambient temperature, -20 Celsius for long term storage
more info or order :
company information
SCICONS
Hosok tere 2, 3044 Szirak
info@scicons.eu
http://scicons.eu
36/1/951-6420
headquarters: Hungary