Peripherin Antibody | Rockland Immunochemicals 900-301-E11 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Peripherin Antibody

catalog :

900-301-E11

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C5

reactivity :

rat

application :

western blot

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

900-301-E11

Name :

Anti-Peripherin (Mouse) Antibody - 900-301-E11

Display Name :

Peripherin Antibody

Application Note :

Anti-Peripherin Antibody is suitable for use in Western Blotting and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 57 kDa in size corresponding to peripherin proteins in the appropriate cell lysate or extract. Anti-Peripherin antibody performs well on aldehyde fixed tissues.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

7C5

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

IF Microscopy Dilution :

1:200

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Prph

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Peripherin Antibody (Monoclonal) was produced by repeated immunizations with recombinant rat peripherin expressed in E. coli.

Packing Type :

Dry Ice

Physical State :

Liquid

Preservative :

0.01% (w/v) Sodium Azide

Purity and Specificity :

Anti-Peripherin antibody is directed against rat Peripherin. The antibody is protein G purified from concentrated clarified cell culture supernate. Reactivity is expected from most mammalian. Cross reactivity with Peripherin from other species is not known.

Species Reactivity :

mouse, rat

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

NEF4, PRPH1, Peripherin, prph, prph1 antibody, PNS antibodies, monoclonal anti-peripherin, mouse monoclonal antibody to peripherin, monoclonal anti-peripherin antibody produced in mouse

Target Species :

Rat

Background :

Peripherin Antibody detects Peripherin. Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. Anti-Peripherin Antibody is ideal for investigators involved in Neuroscience and Cancer research.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Application Text :

IF Microscopy,Western Blot,

Other :

User Optimized

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P21807

Primary Image Name :

Western blot of Anti-Peripherin (Mouse) Antibody - 200-301-E11

more info or order :

Rockland Immunochemicals product webpage