product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
Synapsin I phospho S62 + S67 Antibody
catalog :
612-401-E33
quantity :
100 µL
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
rat
application :
western blot
more info or order :
Rockland Immunochemicals product webpage
product information
Catalog Number :
612-401-E33
Name :
Anti-Synapsin I pS62/pS67 (Rabbit) Antibody - 612-401-E33
Display Name :
Synapsin I phospho S62 + S67 Antibody
Application Note :
Anti-Synapsin I pS62/pS67 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet phosphorylated at Ser62/67 in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
Buffer :
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Clonality :
Polyclonal
Concentration Value :
Titrated value sufficient to run approximately 10 mini blots.
Conjugation :
(None)
Size :
100 µL
Default Unit :
ul
Western Blot Dilution :
1:1000
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG
Gene Name :
Syn1
Host Animal :
Rabbit
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anti-Synapsin I pS62/pS67 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of Synapsin I protein.
Other Performance Data :
Titrated value sufficient to run approximately 10 mini blots.
Packing Type :
Dry Ice
Physical State :
Liquid
Purity and Specificity :
Anti-Synapsin I pS62/67 antibody is directed against rat Synapsin I. Synapsin I pS62/67 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the synapsin I band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding non-phosphophorylated peptide. Reactivity is expected from the following species based on 100% sequence homology: mouse and bovine.
Species Reactivity :
rat
Stabilizer :
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol
Storage :
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Synonyms :
Synapsin I, SYN1, Synapsin-1
Target Species :
Rat
Background :
Synapsin I pS62/67 antibody detects phosphorylated Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase. Anti-Synapsin I pS62/pS67 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Immunogen Type :
Peptide
Low Endotoxin :
No
Post Translational Modification :
Phosphorylation
Sample Size :
No
Target Domain of Reactivity :
Internal
Application Text :
Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
P09951
NCBI :
NP_001104252.1
Primary Image Name :
Western blot of Anti-Synapsin I pS62/pS67 (Rabbit) Antibody - 612-401-E33
more info or order :
Rockland Immunochemicals product webpage
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.