GluR2 phospho S880 Antibody | Rockland Immunochemicals 612-401-D64 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

GluR2 phospho S880 Antibody

catalog :

612-401-D64

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

612-401-D64

Name :

Anti-GluR2 pS880 (Rabbit) Antibody - 612-401-D64

Display Name :

GluR2 phospho S880 Antibody

Application Note :

Anti-GluR2 pS880 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to GluR2 protein phosphorylated at Ser880 in the appropriate cell lysate or extract.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Polyclonal

Concentration Value :

Enough material sufficient for 10 mini blots (total final volume 100 ml at 1:1000 dilution)

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µL

Default Unit :

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Gria2

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-GluR2 pS880 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 880.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-GluR2 pS880 Antibody is directed against phosphorylated rat GluR2 protein at S880. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on 100% sequence homology: human, mouse, non-human primate and Zebrafish.

Species Reactivity :

rat

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Synonyms :

Glutamate receptor 2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

Target Species :

Rat

Background :

GluR2 pS880 Antibody detects phosphorylated rat GluR2 protein. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The number of GluR2 subunits in the AMPA receptor complex affects the Ca2+ permeability, rectification and single-channel conductance of AMPA receptors. Ser880 has been identified as the PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1. GluR2 pS880 antibody is ideal for investigators involved in Neuroscience.

Immunogen Type :

Peptide

Low Endotoxin :

Post Translational Modification :

Phosphorylation

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P19491

NCBI :

AAA41240.1

Primary Image Name :

Western Blot of Anti-GluR2 pS880 (Rabbit) Antibody - 612-401-D64

more info or order :

Rockland Immunochemicals product webpage