product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
GABA(B) Receptor 1 phospho S923 Antibody
catalog :
612-401-D54
quantity :
100 µL
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot
more info or order :
Rockland Immunochemicals product webpage
product information
Catalog Number :
612-401-D54
Name :
Anti-GABA(B) Receptor 1 pS923 (Rabbit) Antibody - 612-401-D54
Display Name :
GABA(B) Receptor 1 phospho S923 Antibody
Application Note :
Anti-GABA(B) Receptor 1 pS923 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 1 protein phosphorylated at Ser923 in the appropriate cell lysate or extract.
Buffer :
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Clonality :
Polyclonal
Concentration Value :
Titrated value sufficient to run approximately 10 mini blots.
Conjugation :
(None)
Size :
100 µL
Default Unit :
ul
Western Blot Dilution :
1:1000
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG
Gene Name :
Gabbr1
Host Animal :
Rabbit
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anti-GABA(B) Receptor 1 pS923 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 923 of rat GABA B R1.
Packing Type :
Dry Ice
Physical State :
Liquid
Purity and Specificity :
Anti-GABA(B) Receptor 1 pS923 Antibody is directed against rat phosphorylated GABA(B) Receptor . The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the GABAB R1 band is completely blocked by lambda-phosphatase treatment. Reactivity is expected from the following species based on 100% sequence homology: bovine, human, mouse and non-human primates.
Species Reactivity :
mouse, rat
Stabilizer :
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol
Storage :
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Synonyms :
Gamma-aminobutyric acid type B receptor subunit 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1
Target Species :
Rat
Background :
GABA(B) Receptor 1 pS923 Antibody detects phosphorylated GABA beta Receptor gamma 1. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser 923 is thought to be important in the regulation of GABAB receptor function. GABA(B) Receptor 1 pS923 antibody is ideal for investigators involved in Neuroscience.
Immunogen Type :
Peptide
Low Endotoxin :
No
Post Translational Modification :
Phosphorylation
Sample Size :
No
Target Domain of Reactivity :
Internal
Application Text :
Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
Q9Z0U4
NCBI :
8393403
Primary Image Name :
Western Blot of Anti-GABA(B) Receptor 1 pS923 (Rabbit) Antibody - 612-401-D54
more info or order :
Rockland Immunochemicals product webpage
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.