Connexin 43 Antibody | Rockland Immunochemicals 612-401-D22 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Connexin 43 Antibody

catalog :

612-401-D22

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

612-401-D22

Name :

Anti-Connexin 43 (Rabbit) Antibody - 612-401-D22

Display Name :

Connexin 43 Antibody

Application Note :

Anti-Connexin 43 Antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 43 kDa in size corresponding to connexin 43 protein in the appropriate cell lysate or extract.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Polyclonal

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Gja1

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Connexin 43 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Connexin 43 antibody is directed against rat Connexin 43. Anti-Connexin 43 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Connexin 43 antibody recognizes Connexin 43 from rat sources. Cross reactivity with Connexin 43 from other species has not been determined. However, reactivity is also expected from the following species based on 100% sequence homology: chicken, canine, finch, human, mouse non-human primate, sheep, Xenopus, zebra fish.

Species Reactivity :

rat

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Synonyms :

Gap junction alpha-1 protein, Gap junction 43 kDa heart protein, CX43, Connexin-43

Target Species :

Rat

Background :

Connexin 43 Antibody detects connexin which is thought to play a key role in development and may also be involved in epilepsy. Connexin 43 antibody recognizes Connexin 43 which forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C. Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability. Anti-Connexin 43 Antibody is ideal for investigators involved in Neuroscience and Cell Signaling.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P08050

NCBI :

AAA41000.1

Primary Image Name :

Western Blot of Anti-Connexin 43 (Rabbit) Antibody - 612-401-D22

more info or order :

Rockland Immunochemicals product webpage