Synapsin I phospho S603 Antibody | Rockland Immunochemicals 612-401-C95 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Synapsin I phospho S603 Antibody

catalog :

612-401-C95

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot

more info or order :

Rockland Immunochemicals product webpage

citations: 1

Reference
Hammond J, Lu S, Gelbard H. Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation. Front Cell Neurosci. 2015;9:505 pubmed publisher

product information

Catalog Number :

612-401-C95

Name :

Anti-Synapsin I pS603 (Rabbit) Antibody - 612-401-C95

Display Name :

Synapsin I phospho S603 Antibody

Application Note :

Anti-Synapsin I pS603 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet protein phosphorylated at Ser603.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Polyclonal

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Syn1

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Synapsin I pS603 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of Synapsin I.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Synapsin I pS603 antibody is directed against bovine Synapsin I. The antibody detects Synapsin I that is phosphorylated at S603. The Anti-Synapsin I pS603 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the synapsin I band is blocked by lambda-phosphatase treatment. Reactivity is expected from the following species based on 100% sequence homology: human, Xenopus, bovine, zebra fish.

Species Reactivity :

mouse, rat

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Synonyms :

Synapsin I, SYN1, Synapsin-1

Target Species :

Rat

Background :

Synapsin I pS603 antibody is directed against rat Synapsin I, whcih plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases. Phosphorylation of this site is thought to regulate synaptic vesicle function. Anti-Synapsin I pS603 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Immunogen Type :

Peptide

Low Endotoxin :

Post Translational Modification :

Phosphorylation

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P09951

NCBI :

NP_001104252.1

Primary Image Name :

Western blot of Synapsin I Ser603 Antibody

more info or order :

Rockland Immunochemicals product webpage