product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
BICD1 Antibody
catalog :
600-401-Z62
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA
product information
Catalog Number :
600-401-Z62
Name :
Anti-BICD1 (RABBIT) Antibody - 600-401-Z62
Display Name :
BICD1 Antibody
Application Note :
Anti-BICD1 Antibody has been tested for use in ELISA, Western Blotting, Immunocytochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 111 kDa in Western Blots of specific cell lysates and tissues.
Buffer :
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Clonality :
Polyclonal
Concentration Value :
1 mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
100 µg
Default Unit :
µg
ELISA Dilution :
1:10,000
IF Microscopy Dilution :
10 µg/mL
Western Blot Dilution :
1 µg/mL
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG
Gene Name :
BICD1
Host Animal :
Rabbit
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anti-BICD1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the C-terminus of human BICD1.
Packing Type :
Dry Ice
Physical State :
Liquid (sterile filtered)
Preservative :
0.02% (w/v) Sodium Azide
Purity and Specificity :
Anti-BICD1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.
Species Reactivity :
Human, mouse, rat
Storage :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Synonyms :
BICD1 Antibody, BICD, Protein bicaudal D homolog 1, Bic-D 1
Target Species :
Human
Background :
BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
Immunogen Type :
Peptide
Low Endotoxin :
No
Sample Size :
No
Target Domain of Reactivity :
C-Terminus
Application Text :
ELISA,IF Microscopy,Western Blot,
Other :
Immunocytochemistry: 2.5 µg/mL
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
Q96G01
NCBI :
NP_001705
Primary Image Name :
Western Blot of BICD1 Antibody
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.