Ribosomal S6 Kinase 2 Antibody | Rockland Immunochemicals 600-401-X25 product information

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product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Ribosomal S6 Kinase 2 Antibody

catalog :

600-401-X25

quantity :

100 µL

price :

366 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, ELISA

product information

Catalog Number :

600-401-X25

Name :

Anti-Ribosomal S6 kinase 2 (RABBIT) Antibody - 600-401-X25

Display Name :

Ribosomal S6 Kinase 2 Antibody

Application Note :

Anti-Ribosomal S6 Kinase 2 Antibody is stored with 100 μg per ml BSA. It is suitable for Western Blots and is specific for the ~90 kDa RSK2 protein. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Polyclonal

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Rps6ka2

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Ribosomal S6 Kinase 2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region of mouse Ribosomal S6 Kinase 2 conjugated to KLH.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Purity and Specificity :

Anti-Ribosomal S6 Kinase 2 Antibody was prepared from rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as an antigen.

Species Reactivity :

Mouse, Bovine, Canine, Chicken, Human, Non-human primates, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilut

Synonyms :

Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase MpK-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3

Target Species :

Mouse

Background :

The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling. Ribosomal S6 Kinase 2 Antibody is ideal for researchers interested in neuroscience research.

General Reference :

Hanauer A, Young ID (2002) Coffin-Lowry syndrome: clinical and molecular features. J Med Genet 39:705-713. Sheffler DJ, Kroeze WK, Garcia BG, Deutch AY, Hufeisen SJ, Leahy P, Bruning JC, Roth BL (2006) p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc Natl Acad Sci (USA) 103:4717-4722.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

2020 Price :

366 USD

UniProt :

Q9WUT3

NCBI :

NP_035429.1