BETA 1 ADRENERGIC RECEPTOR Antibody | Rockland Immunochemicals 600-401-MH1 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

BETA 1 ADRENERGIC RECEPTOR Antibody

catalog :

600-401-MH1

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, flow cytometry

more info or order :

Rockland Immunochemicals product webpage

image

image 1 :

Flow Cytometry of Rabbit Anti-Beta 1 Adrenergic Receptor Antibody. Cells: NCCIT cells. Primary Antibody: Beta 1 Adrenergic Receptor Antibody at 5µL in 100µL FACS buffer for 30 mins at RT. Secondary Antibody: Donkey Anti-DyLight™488 (p/n 611-741-127) at 1:400 for 30 mins at RT.

product information

Catalog Number :

600-401-MH1

Name :

Anti-BETA 1 ADRENERGIC RECEPTOR (RABBIT) Antibody - 600-401-MH1

Display Name :

BETA 1 ADRENERGIC RECEPTOR Antibody

Application Note :

Anti-beta 1 adrenergic Antibody has been tested in ELISA, WB, and FLOW. Expect a band at ~51kDa in western blot using appropriate lysates. Positive control used: human heart muscle membrane tissues in WB and NCCIT cells in FLOW. Although not tested, this antibody may be suitable in IHC.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

0.97 mg/ml

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000 - 1:15,000

Flow Cytometry Dilution :

1:20

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

ADRB1

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-BETA 1 ADRENERGIC RECEPTOR (RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human beta 1 adrenergic conjugated to Keyhole Limpet Hemocyanin (KLH).

Other Performance Data :

User Optimized

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.01% (w/v) Sodium Azide

Purity and Specificity :

This affinity purified antibody is directed against human beta 1 adrenergic. This product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to human, mouse, rat, and rhesus macaque.

Species Reactivity :

Human

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

Rabbit Anti-Beta-1 Adrenergic receptor Antibody, Rabbit Anti-Adrenergic ß1R Antibody, Adrenoceptor Beta 1, Adrenergic Beta-1-Receptor, Beta-1 Adrenoreceptor, Beta-1 Adrenoceptor, Adrb1r, B1AR, Beta-1 Adrenergic Receptor, BETA1AR, RHR, Beta-1 adrenergic receptor

Target Species :

Human

Background :

The adrenergic beta1 receptor (beta1-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta2 and beta3. They are located primarily in the CNS, heart, coronary artery, kidney and muscle. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Anti-beta 1 andrenergic receptor Antibody is useful for researchers interested in cardiac function and G-protein signaling pathways.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

ELISA,Flow Cytometry,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P08588

NCBI :

NP_000675.1

Primary Image Name :

Flow Cytometry of Rabbit Anti-Beta 1 Adrenergic Receptor Antibody

more info or order :

Rockland Immunochemicals product webpage