Avian Influenza Neuraminidase Antibody | Rockland Immunochemicals 600-401-G80 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Avian Influenza Neuraminidase Antibody

catalog :

600-401-G80

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

600-401-G80

Name :

Anti-Avian Influenza Neuraminidase (RABBIT) Antibody - 600-401-G80

Display Name :

Avian Influenza Neuraminidase Antibody

Application Note :

Anti-Avian Influenza Neuraminidas Antibody is suitable for use in ELISA. Expect a band approximately ~51.4 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

1 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1 ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Avian Influenza Neuraminidase Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to an internal region of the avian influenza neuraminidase protein. Efforts were made to use relatively conserved regions as the antigen.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.01% (w/v) Sodium Azide

Purity and Specificity :

Anti-Avian Influenza Neuraminidase Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Avian Influenza Neuraminidase with Virus based on 100% homology with the immunizing sequence. Cross-reactivity with Avian Influenza Neuraminidase from other sources has not been determined.

Species Reactivity :

Virus

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

Neuraminidase

Background :

Avian Influenza Neuraminidase Antibody detects internal portion of the protein. Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus. Anti-Avian Influenza Neuraminidase antibodies are ideal for investigators involved in infectious disease reseach.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

ELISA,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q692M2

NCBI :

AAT76166

more info or order :

Rockland Immunochemicals product webpage