TLR4 Antibody | Rockland Immunochemicals 600-401-G52 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

TLR4 Antibody

catalog :

600-401-G52

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

600-401-G52

Name :

Anti-TLR4 (RABBIT) Antibody - 600-401-G52

Display Name :

TLR4 Antibody

Application Note :

Anti-TLR4 Antibody is suitable for use in WB, IHC, IF microscopy and Flow Cytometry. Expect a band approximately ~75-80kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag). Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

1.0 mg/ml

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

1:50

IF Microscopy Dilution :

User Optimized

Western Blot Dilution :

1-3ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

TRL4

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

TRL4 Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against synthetic peptide corresponding to an internal region of human TLR4.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.5% (w/v) Sodium Azide

Purity and Specificity :

Anti-TLR4 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with TRL 4 from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TRL4 from other sources has not been determined. Cell Signaling research.

Species Reactivity :

Human, Mouse

Stabilizer :

10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

ARMD10, CD284, TLR 4, TOLL, Toll like receptor 4

Target Species :

Human

Background :

The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediatiors of LPS signaling. The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

Immunohistochemistry,IF Microscopy,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

O00206

NCBI :

NP_612564.1

Primary Image Name :

TLR4 Immunofluorescence

more info or order :

Rockland Immunochemicals product webpage