product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
TLR8 Antibody
catalog :
600-401-FG4
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry
product information
Catalog Number :
600-401-FG4
Name :
Anti-TLR8 (RABBIT) Antibody - 600-401-FG4
Display Name :
TLR8 Antibody
Application Note :
Anti-TLR8 Antibody has been tested for use in ELISA, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 120 kDa in Western Blots of specific cell lysates and tissues.
Buffer :
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Clonality :
Polyclonal
Concentration Value :
1 mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
100 µg
Default Unit :
µg
ELISA Dilution :
User Optimized
Immunohistochemistry Dilution :
5 μg/mL
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG
Gene Name :
TLR8
Host Animal :
Rabbit
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anti-TLR8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the N-terminus of human TLR8.
Packing Type :
Dry Ice
Physical State :
Liquid (sterile filtered)
Preservative :
0.02% (w/v) Sodium Azide
Purity and Specificity :
Anti-TLR8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members
Species Reactivity :
Human
Storage :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Synonyms :
TLR8 Antibody, CD288, Toll-like receptor 8
Target Species :
Human
Background :
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.
Immunogen Type :
Peptide
Low Endotoxin :
No
Sample Size :
No
Target Domain of Reactivity :
N-Terminus
Application Text :
ELISA,Immunohistochemistry,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
Q9NR97
NCBI :
NP_619542.1
Primary Image Name :
Immunohistochemistry of TLR8 Antibody
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.