Hsp110 Antibody | Rockland Immunochemicals 600-401-F52 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Hsp110 Antibody

catalog :

600-401-F52

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

600-401-F52

Name :

Anti-Hsp110 (RABBIT) Antibody - 600-401-F52

Display Name :

Hsp110 Antibody

Application Note :

Anti-Hsp110 Antibody is suitable for use in WB, IHC, and IF/ICC. Expect a band approximately ~110kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

1:100

IF Microscopy Dilution :

User Optimized

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

HSPH1

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Hsp110 Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against a synthetic peptide derived from the sequence of hamster Hsp110.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-Hsp110 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Hsp110 from Human, Monkey, Hamster, Rat, Mouse, Cow, Sheep, and Yeast based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp110 from other sources has not been determined. Heat Shock research.

Species Reactivity :

Human, Monkey, Hamster, Rat, Mouse, Bovine, Sheep, Yeast

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

Heat shock 105kDa alpha, heat shock 105kDa beta, Hsp105, Hsp105A, Hsp105B, Hsp110, HSPH1, NY CO 25, Heat shock 110 kDa protein

Target Species :

Armenian Hamster

Background :

Hsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain. Hsp110 cooperates with Hsp70 in protein folding in the eukaryotic cytosol. In mammals, Hsp110 is constitutively expressed, but exhibits particularly high levels in the brain. Both Hsp70 and Hsp110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of Hsp110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70. Studies also suggest that Hsp110 can be used in heat shock protein-based cancer immunotherapy.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

Immunohistochemistry,IF Microscopy,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q60446

NCBI :

NP_001233649.1

Primary Image Name :

Hsp110 Western Blot

more info or order :

Rockland Immunochemicals product webpage