Tyrosine Hydroxylase phospho S40 Antibody | Rockland Immunochemicals 600-401-C99 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Tyrosine Hydroxylase phospho S40 Antibody

catalog :

600-401-C99

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

600-401-C99

Name :

Anti-Tyrosine Hydroxylase pS40 (Rabbit) Antibody - 600-401-C99

Display Name :

Tyrosine Hydroxylase phospho S40 Antibody

Application Note :

Anti-Tyrosine Hydroxylase pS40 antibody is suitable for use in ELISA, Western Blotting, IHC and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 42/44 kDa in size corresponding to the tyrosine hydroxylase proteins phosphorylated at Ser40 in the appropriate cell lysate or extract. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Polyclonal

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:10,000

Immunohistochemistry Dilution :

1:1000

IF Microscopy Dilution :

1:1000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Tyrosine Hydroxylase pS40 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 40 conjugated to KLH.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Tyrosine Hydroxylase pS40 antibody is affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: mouse. Cross reactivity from Tyrosine Hydroxylase pS40 from other sources has not been determined.

Species Reactivity :

mammalian, non-mammalian

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Synonyms :

Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH

Target Species :

Rat

Background :

Tyrosine Hydroxylase pS40 antibody recognizes Tyrosine hydroxylase (TH) which is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs. Tyrosine Hydroxylase pS40 antibody is ideal for investigators involved in Neuronal Circuitry and disorders, and more generally in Neuroscience.

Immunogen Type :

Peptide

Low Endotoxin :

Post Translational Modification :

Phosphorylation

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

ELISA,Immunohistochemistry,IF Microscopy,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P04177

NCBI :

NP_036872.1

Primary Image Name :

Western blot of Tyrosine Hydroxylase Ser40 Antibody

more info or order :

Rockland Immunochemicals product webpage