IL-34 Antibody | Rockland Immunochemicals 600-401-C06 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

IL-34 Antibody

catalog :

600-401-C06

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

600-401-C06

Name :

Anti-IL-34 (Rabbit) Antibody - 600-401-C06

Display Name :

IL-34 Antibody

Application Note :

Anti-IL-34 Antibody has been tested for use in ELISA and WB. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~48 kDa in size corresponding to IL-34 by Western blotting in the appropriate cell lysate or extract. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE. Human brain tissue lysate may be used as positive control.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

1.0 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000 - 1:40,000

Western Blot Dilution :

0.25 - 0.5 µg/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

IL34

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-IL-34 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human IL-34 protein.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.01% (w/v) Sodium Azide

Purity and Specificity :

Anti-IL 34 was purified from monospecific antiserum by immunoaffinity chromatography. The IL34 gene is conserved in chimpanzee, dog, cow, mouse, and rat. This antibody reacts with IL-34 from human, mouse, and rat sources. Reactivity with IL-34 from other sources has not been determined.

Species Reactivity :

Human, mouse, rat

Storage :

Store IL-34 Antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

IL-34, Interleukin-34

Target Species :

Human

Background :

Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Anti-IL-34 Antibody is ideal for investigators involved in Cell Signaling, Immunology and Signal Transduction research.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

N-Terminus

Application Text :

ELISA,Western Blot,

Other :

User Optimized

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q6ZMJ4

NCBI :

187610438

Primary Image Name :

Anti-IL-34 Antibody - Western Blot

more info or order :

Rockland Immunochemicals product webpage