Tubulin beta 3 Antibody | Rockland Immunochemicals 212-301-E55 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Tubulin beta 3 Antibody

catalog :

212-301-E55

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AA10

reactivity :

rat

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

212-301-E55

Name :

Anti-Tubulin beta 3 (Mouse) Antibody - 212-301-E55

Display Name :

Tubulin beta 3 Antibody

Application Note :

Anti-Tubulin beta 3 (Mouse) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Monoclonal

Clone ID :

AA10

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

Immunohistochemistry Dilution :

1:1,000

Western Blot Dilution :

1:10,000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG

Gene Name :

Tubb3

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein. The antibody was Protein G purified from cell culture supernatant. Cross reactivity with tubulin beta 3 from other species has not been determined.

Species Reactivity :

rat

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Subclass :

IgG

Synonyms :

mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Target Species :

Rat

Background :

Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

Immunohistochemistry,Western Blot,

Other :

User Optimized

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q4QRB4

NCBI :

AAM28438.1

Primary Image Name :

Immunohistochemistry - Mouse Anti-Tubulin B III antibody

more info or order :

Rockland Immunochemicals product webpage