Thyroid Hormone Receptor alpha 2 Antibody | Rockland Immunochemicals 209-301-E44 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Thyroid Hormone Receptor alpha 2 Antibody

catalog :

209-301-E44

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1330

reactivity :

human, rat

application :

western blot

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

209-301-E44

Name :

Anti-Thyroid Hormone Receptor alpha 2 (Mouse) Monoclonal Antibody - 209-301-E44

Display Name :

Thyroid Hormone Receptor alpha 2 Antibody

Application Note :

Anti-Thyroid Hormone Receptor alpha 2 antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band or approximately 58 kDa in size corresponding to TR-α2 proteins in the appropriate cell lysate or extract.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Monoclonal

Clone ID :

1330

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

THRA

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha 2.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody is directed against human thyroid hormone receptor alpha 2 protein. Thyroid Hormone Receptor alpha 2 antibodies are purified by Protein G chromatography from cell culture supernatant. Reactivity is expected from the following species based on 100% sequence homology: bovine, mouse and rat tissues. Cross reactivity from other sources has not been tested.

Species Reactivity :

human, rat

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

mouse anti-Thyroid Hormone Receptor alpha 2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha

Target Species :

Human

Background :

Thyroid Hormone Receptor alpha 2 antibody detects TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα2 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

N-Terminus

Application Text :

Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P10827

NCBI :

NP_001177848.1

Primary Image Name :

Western blot of Anti-Thyroid Hormone Receptor alpha 2 (Mouse) Antibody - 209-301-E44

more info or order :

Rockland Immunochemicals product webpage