TLR4 Antibody | Rockland Immunochemicals 200-501-I26 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

TLR4 Antibody

catalog :

200-501-I26

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MTS510

reactivity :

mouse

application :

western blot, flow cytometry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-501-I26

Name :

Anti-TLR4 (RAT) Monoclonal Antibody - 200-501-I26

Display Name :

TLR4 Antibody

Application Note :

Anti-TLR4 Antibody is suitable for use in FA (N), Flow (CS) and IP. Expect a band approximately 95kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

MTS510

Concentration Value :

0.5 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Flow Cytometry Dilution :

2-5 µg/10^6 cells

Western Blot Dilution :

1:500-1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG2a

Gene Name :

Tlr4

Host Animal :

Rat

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

TLR4 Antibody was produced in rats prepared by repeated immunizations with the Ba/F3 cell line expressing mouse protein TLR4.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-TLR4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR4 from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR4 from other sources has not been determined. Toll Like Receptors and signaling research.

Species Reactivity :

Mouse

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG2a

Synonyms :

hToll, Toll-like receptor 4, CD284

Target Species :

Mouse

Background :

Anti-TLR4 CD284 Antibody detects human TLR4. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Among this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling. The TLR4 cDNA codes for a protein consisting of 799 amino acids with approximate molecular weight of 88 kDa. Anti-TLR4 CD284 Antibody is ideal for invedtigators invovled in cytokines and growth factor research.

Immunogen Type :

Other

Low Endotoxin :

Sample Size :

Application Text :

Flow Cytometry,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q9QUK6

NCBI :

NP_067272.1

Primary Image Name :

TLR4 Flow Cytometry

more info or order :

Rockland Immunochemicals product webpage