Jagged 1 Antibody | Rockland Immunochemicals 200-401-698 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Jagged 1 Antibody

catalog :

200-401-698

quantity :

500

price :

564.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Rockland Immunochemicals product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; loading ...; fig s10	Boareto M, Jolly M, Goldman A, Pietila M, Mani S, Sengupta S, et al. Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype. J R Soc Interface. 2016;13: pubmed publisher

product information

Catalog Number :

200-401-698

Name :

Anti-Jagged-1 (RABBIT) Antibody - 200-401-698

Display Name :

Jagged 1 Antibody

Application Note :

Anti-Jagged-1 antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence microscopy and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 150 kDa in size corresponding to Jagged-1 in mouse liver, human liver and human lung whole cell lysates.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

1.15 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

500

Default Unit :

µg

ELISA Dilution :

1:20,000 - 1:100,000

Immunohistochemistry Dilution :

1:100 - 1:500

IF Microscopy Dilution :

1:200 - 1:1,000

Western Blot Dilution :

1:500 - 1:2,000

Expiration :

Expiration date is one (1) year from date of receipt.

Format :

IgG

Gene Name :

JAG1

Harmonization Code :

3002.14.0000

UNSPSC :

Antibodies

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

This protein A purified Jagged 1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the N-terminus of human Jagged-1 protein.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.01% (w/v) Sodium Azide

Purity and Specificity :

This protein A purified antibody is directed against human Jagged-1 protein. The product was purified from mono-specific antiserum by affinity chromatography. A BLAST analysis was used to suggest cross reactivity with Jagged-1 protein from human, chimpanzee, rat and mouse based on 100% homology with the immunizing sequence. Partial reactivity is expected against dog (81%) and Xenopus laevis (85%) based on partial sequence homologies as indicated. Reactivity against homologues from other sources is not known.

Species Reactivity :

Human; Mouse

Tested Applications :

ELISA; IF; IHC; WB

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

rabbit anti-Jagged 1 Antibody, rabbit anti-Jagged1 Antibody, rabbit anti-Jagged-1 Antibody, Ser 1 antibody, AGS antibody, AHD antibody, AWS antibody, CD 339 antibody, CD339 antibody, CD339 antigen antibody, Headturner antibody, HJ1 antibody, Htu antibody

Target Species :

Human

Background :

Anti-Jagged 1 Antibody recognizes the Jagged 1 protein encoded by the JAG1 gene, that is the human homolog of the Drosophilia jagged protein. Human Jagged 1 is the ligand for multiple Notch receptors and mediation of Notch signaling. Jagged 1 signaling through Notch 1 has also been shown to play a role in hematopoiesis. Mutations that alter the Jagged 1 protein cause Alagille syndrome, deafness, congenital heart defects, and posterior embryotoxon. Anti-Jagged-1 Antibody is useful for researchers interested in Notch activation, Growth Factor activities, and Cardiovascular health.

Immunogen Type :

Conjugated Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

ELISA,Immunohistochemistry,IF Microscopy,Western Blot,

Other :

User Optimized

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

2026 Price :

564.00 USD

UniProt :

P78504

NCBI :

4557679

Primary Image Name :

Immunofluorescence Microscopy

more info or order :

Rockland Immunochemicals product webpage