OCRL/INPP5F Antibody ATTO 633 | Rockland Immunochemicals 200-360-W76 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

OCRL/INPP5F Antibody ATTO 633

catalog :

200-360-W76

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S166A-26

reactivity :

human, mouse, rat

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-360-W76

Name :

Anti-OCRL/INPP5b (MOUSE) Monoclonal Antibody ATTO 633 Conjugated - 200-360-W76

Display Name :

OCRL/INPP5F Antibody ATTO 633

Application Note :

Anti-OCRL/INPP5F ATTO 633 Conjugated Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately ~100kDa on specific lysates or tissues. Does cross react with INPP5b. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S166A-26

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

AT633

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

OCRL

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-OCRL/INPP5F Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-901 (full length) of human INPP5F.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-OCRL/INPP5F Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 93% identical to rat, 91% identical to mouse and ~50% identical to INPP5b.

Species Reactivity :

Human, Rat, Mouse

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

EC 3.1.3.36 antibody, Inositol polyphosphate 5 phosphatase OCRL 1 antibody, Lowe oculocerebrorenal syndrome protein antibody, INPP5F antibody, LOCR antibody

Target Species :

Human

Background :

Inositol polyphosphate 5-phosphatase OCRL-1 (INPP5F/OCRL) is also called Lowe oculocerebrorenal syndrome protein. INPP5F is a phosphotase that converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate, as well as inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. ORCL is involved in primary cilia assembly and may also have a role in lysosomal membrane trafficking. ORCL is expressed in brain, skeletal muscle, heart, kidney, lung, placenta, fibroblasts, retina and the retinal pigment epithelium. INPP5F defects can cause Lowe oculocerebrorenal syndrome (OCRL) and Dent disease type 2 (DD2). Anti-OCRL/INPP5F is ideal for research in Neuroscience, including research in Alzheimer's disease and D-myo-inositol (1,3,4)-triphosphate biosynthesis, and Cell Biology.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

ATTO 633

UniProt :

Q01968

NCBI :

NP_000267

more info or order :

Rockland Immunochemicals product webpage