Protocadherin Gamma A (pan) Antibody ATTO 633 | Rockland Immunochemicals 200-360-W67 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Protocadherin Gamma A (pan) Antibody ATTO 633

catalog :

200-360-W67

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S144-32

reactivity :

mouse, rat

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-360-W67

Name :

Anti-Protocadherin Gamma A (pan) (MOUSE) Monoclonal Antibody ATTO 633 Conjugated - 200-360-W67

Display Name :

Protocadherin Gamma A (pan) Antibody ATTO 633

Application Note :

Anti-Protocadherin Gamma A (pan) ATTO 633 Conjugated Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately ~100 kDa on specific lysates or tissues. It will cross react with other Gamma-protocadherin-A proteins, but it won't cross react with any Gamma-protocadherin -B or -C proteins. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S144-32

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

AT633

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG2b

Gene Name :

Pcdhga3

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Protocadherin Gamma A (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 720-804 of mouse Gamma-Protocadherin A3

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-Protocadherin Gamma A (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 80% identical to human and >75% identical to other Gamma-Protocadherin-A proteins.

Species Reactivity :

Mouse, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG2b

Synonyms :

PCDH gamma A antibody, PCDH-gamma-A, PCDHGA, Protocadherin gamma A, Protocadherin gamma subfamily A, Gamma Protocadherin A (pan), Pan-Gamma-Protocadherin-A, Pan Gamma Protocadherin A

Target Species :

Mouse

Background :

The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. Anti-Protocadherin Gamma A (pan) is ideal for research in Neuroscience, Cell Adhesion, and Cell Signaling.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Internal

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

ATTO 633

UniProt :

Q91XY5

NCBI :

NP_291064

more info or order :

Rockland Immunochemicals product webpage