LRRK2/Dardarin Antibody ATTO 633 | Rockland Immunochemicals 200-360-W60 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

LRRK2/Dardarin Antibody ATTO 633

catalog :

200-360-W60

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S138-6

reactivity :

human, mouse, rat

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-360-W60

Name :

Anti-LRRK2/Dardarin (MOUSE) Monoclonal Antibody ATTO 633 Conjugated - 200-360-W60

Display Name :

LRRK2/Dardarin Antibody ATTO 633

Application Note :

Anti-LRRK2/Dardarin ATTO 633 Conjugated Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately >200 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S138-6

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

AT633

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

LRRK2

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-LRRK2/Dardarin Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-500 of human LRRK2.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-LRRK2/Dardarin Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests 83% similarity to mouse, 83% similarity to rat and no similarity to LRRK1.

Species Reactivity :

Human, Rat, Mouse

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

Leucine-rich repeat kinase 2, RIP7, PARK8, Dardarin, ROCO 2, RIPK7, Leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 40

Target Species :

Human

Background :

LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

N-Terminus

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

ATTO 633

UniProt :

Q5S007

NCBI :

NP_940980

more info or order :

Rockland Immunochemicals product webpage